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Establishment of alternative exercise methods for maintaining or improving cognitive function

Research Project

Project/Area Number 15K16535
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionHyogo University of Health Sciences

Principal Investigator

Miyamoto Toshiaki  兵庫医療大学, リハビリテーション学部, 講師 (30709340)

Research Collaborator Moritani Toshio  京都大学, 名誉教授 (90175638)
Iwakura Toshio  神戸市立医療センター中央市民病院, 糖尿病内分泌内科, 医長
Matsuoka Naoki  神戸市立医療センター中央市民病院, 糖尿病内分泌内科, 部長
Iwamoto Masako  神戸市立医療センター中央市民病院, 栄養管理部, 主査
Takenaka Mariko  神戸市立医療センター中央市民病院, 栄養管理部, 管理栄養士
Fujioka Hiroyuki  兵庫医療大学, リハビリテーション学部, 教授 (10252777)
Takeda Chisako  兵庫医療大学, 看護学部, 教授 (10148273)
Kashiwamura Shin-ichiro  兵庫医療大学, 共通教育センター, 教授 (00185761)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords神経筋電気刺激 / 脳由来神経栄養因子 / 運動 / 認知機能 / 二重課題 / 脳由来神経使用因子 / 乳酸 / 高速度自転車運動 / 骨格筋電気刺激 / 認知症 / 脳由来性神経栄養因子 / 身体活動
Outline of Final Research Achievements

This study examined the effects of neuromuscular electrical stimulation, combining cognitive and physical exercise, and low-resistance and high-velocity ergometry exercise to brain-derived neurotrophic factor to establish new exercise methods for maintaining or improving cognitive function. This study showed that brain-derived neurotrophic factor significantly increased during neuromuscular electrical stimulation or low-resistance and high-velocity ergometry exercise, and that there was no synergistic response of brain-derived neurotrophic factor to combining cognitive and physical exercise. This study suggested that neuromuscular electrical stimulation or low-resistance and high-velocity ergometry exercise may have potential to be alternative exercise methods since brain-derived neurotrophic factor is potential mediators responsible for the beneficial effects of physical exercise on cognitive function.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2018 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Journal Article] Response of Brain-derived Neurotrophic Factor to Combining Cognitive and Physical Exercise2018

    • Author(s)
      Miyamoto T, Hashimoto S, Yanamoto H, Ikawa M, Nakano Y, Sekiyama T, Kou K, Kashiwamura S, Takeda C, Fujioka H
    • Journal Title

      Eur J Sport Sci.

      Volume: - Issue: 8 Pages: 1119-1127

    • DOI

      10.1080/17461391.2018.1470676

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Neuromuscular Electrical Stimulation on Brain-derived Neurotrophic Factor2018

    • Author(s)
      Miyamoto T, Kou K, Yanamoto H, Hashimoto S, Ikawa M, Sekiyama T, Nakano Y, Kashiwamura S, Takeda C, Fujioka H
    • Journal Title

      Int J Sports Med

      Volume: 39 Issue: 01 Pages: 5-11

    • DOI

      10.1055/s-0043-120343

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] Response of Brain-derived Neurotrophic Factor to High-speed and Low-resistance Cycling Exercise in Healthy Adults: A Randomized Controlled Trial2018

    • Author(s)
      Miyamoto T, Nishiwaki E, Uho T, Mizutani R, Masuda M, Takeda C, Fujioka H
    • Organizer
      23rd annual Congress of the European College of Sport Science
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Acute Response of Plasma Brain-Derived Neurotrophic Factor to Neuromuscular Electrical Stimulation in Healthy Adults2017

    • Author(s)
      Miyamoto T, Kou K, Hashimoto S, Yanamoto H, Ikawa M, Sekiyama T, Nakano Y, Kashiwamura S, Takeda C, Fujioka H
    • Organizer
      WCPT-AWP & PTAT Congress 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 神経筋電気刺激療法は心臓リハビリテーションの補足・代替療法になり得るか?血糖コントロールに対する神経筋電気刺激療法の可能性2016

    • Author(s)
      宮本俊朗、森谷敏夫
    • Organizer
      第22回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-07-16
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Prolonged Electrical Muscle Stimulation Increases Plasma Brain-Derived Neurotrophic Factor in Type 2 Diabetes2016

    • Author(s)
      Miyamoto T, Iwakura T, Morino T, Iwamoto M, Takenaka M, Akamatsu Y, Moritani T
    • Organizer
      21st annual Congress of the European College of Sport Science
    • Place of Presentation
      Austria Center Vienna (Vienna, Austria)
    • Year and Date
      2016-07-06
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 継続的な骨格筋電気刺激の使用が2型糖尿病患者の糖・脂質代謝に与える影響 ランダム化クロスオーバー比較試験2016

    • Author(s)
      宮本俊朗、岩倉敏夫、森野隆弘、岩本昌子、竹中麻理子、松岡直樹、森谷敏夫
    • Organizer
      第51回日本理学療法学術大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-05-27
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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