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Prospective study of trajectories of physical performance and associated factors among Older Japanese

Research Project

Project/Area Number 15K16539
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionTokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Principal Investigator

Taniguchi Yu  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (40636578)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords加齢 / 老化 / 身体機能 / 加齢変化パターン / 加齢変化
Outline of Final Research Achievements

Among 1524 adults aged 65 years or older who participated in a baseline survey, 1048 adults (mean [SD] age, 71.6 [5.4] years; women, 57.0%) were followed-up at least once. The total number of observations was 4,747, and the average number of follow-up assessments was 4.5 during the period from 2002 through 2010. We checked local registries to identify deaths from any cause; 89 (8.5%) participants died until 2011.
We identified 3 distinct trajectory patterns (high, middle, and low trajectory groups) for each PPM (hand-grip strength, usual gait speed, and one-leg standing time) in adults aged 65 to 90 years, and the trajectories for hand-grip strength and usual gait speed showed parallel declines in men and women, respectively. Adults in the low trajectory group were more likely to be lower BMIs, hemoglobin A1c values, albumin levels, TMIG-IC scores, and scores.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (26 results)

All 2017 2016 2015

All Journal Article (13 results) (of which Int'l Joint Research: 8 results,  Peer Reviewed: 13 results,  Open Access: 9 results,  Acknowledgement Compliant: 10 results) Presentation (13 results) (of which Int'l Joint Research: 4 results,  Invited: 2 results)

  • [Journal Article] Gait performance trajectories and incidence of dementia2017

    • Author(s)
      Taniguchi Y, Kitamura A, Seino S, Murayama H, Amano H, Nofuji Y, Nishi M, Yokoyama Y, Shinozaki T, Yokota I, Matsuyama Y, Fujiwara Y, Shinkai S
    • Journal Title

      J Am Med Dir Assoc

      Volume: 印刷中 Issue: 2 Pages: 192.e13-192.e20

    • DOI

      10.1016/j.jamda.2016.10.015

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 身体機能と将来の認知症との関連2017

    • Author(s)
      谷口優
    • Journal Title

      日本老年社会科学

      Volume: 39 Pages: 72-78

    • NAID

      40021195468

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mini-Mental State Examination Score Trajectories and Incident Disabling Dementia Among Community-Dwelling Older Japanese2017

    • Author(s)
      Taniguchi Y, Kitamura A, Murayama H, Amano H, Shinozaki T, Yokota I, Seino S, Nofuji Y, Nishi M, Yokoyama Y, Matsuyama Y, Fujiwara Y, Shinkai S
    • Journal Title

      Geriatr Gerontol Int

      Volume: 印刷中 Issue: 11 Pages: 1928-1935

    • DOI

      10.1111/ggi.12996

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Public health approach to preventing frailty in the community and its effect on healthy aging in Japan2016

    • Author(s)
      Shinkai S, Yoshida H, Taniguchi Y, Murayama H, Nishi M, Amano H, Nofuji Y, Seino S, Fujiwara Y
    • Journal Title

      Geriatr Gerontol Int

      Volume: 16 Issue: S1 Pages: 87-97

    • DOI

      10.1111/ggi.12726

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age-related disorders2016

    • Author(s)
      Yasunori Fujita, Yu Taniguchi, Shoji Shinkai, Masashi Tanaka, Masafumi Ito
    • Journal Title

      Geriatr Gerontol Int

      Volume: 16 (Suppl. 1) Issue: S1 Pages: 17-29

    • DOI

      10.1111/ggi.12724

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Associations of Walking Speed, Grip Strength, and Standing Balance with Total and Cause-Specific Mortality in a General Population of older Japanese.2016

    • Author(s)
      Yu Nofuji, Shoji Shinkai, Yu Taniguchi, Hidenori Amano, Mariko Nishi, Hiroshi Murayama, Yoshinori Fujiwara, Takao Suzuki.
    • Journal Title

      Journal of the American Medical Directors Association

      Volume: 17

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Frailty predicts trajectories of quality of life over time among British community-dwelling older people.2016

    • Author(s)
      Gotaro Kojima, Steve Iliffe, Richard W Morris, Yu Taniguchi, Denise Kendrick, Dawn A Skelton, Tahir Masud, Ann Bowling.
    • Journal Title

      Quality of Life Research

      Volume: 2 Issue: 7 Pages: 1743-1750

    • DOI

      10.1007/s11136-015-1213-2

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Frailty as a Predictor of Alzheimer’s Disease, Vascular Demantia, and All Dementia Among Community-Dwelling Older People.A Systematic Review and Meta-Analysis.2016

    • Author(s)
      Gotaro Kojima, Yu Taniguchi, Steve Iliffe, Kate Walters.
    • Journal Title

      Journal of the American Medical Directors Association

      Volume: 27 Pages: 881-888

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Prevalence of Frailty in Japan.A Systematic Review and Meta-analysis.2016

    • Author(s)
      Gotaro Kojima, Steve Iliffe, Yu Taniguchi, Hiroyuki Shimada, Hiromi Rakugi, Kate Walters.
    • Journal Title

      Journal of Epidemiology

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Albmin, Hemoglobin, and the Trajectory of Cognitive Function in Community-Dwelling Older Japanese: A 13-Year Longitudinal Study.2016

    • Author(s)
      Hiroshi Murayama, Shoji Shinkai, Mariko Nishi, Yu Taniguchi, Hidenori Amano, Satoshi Seino, Yuri Yokoyama, Hiroto Yoshida, Yoshinori Fujiwara, Hideki Ito.
    • Journal Title

      The Journal of Prevention of Alzheimer’s Disease

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Prospective Study of Arterial Stiffness and Subsequent Cognitive Decline Among Community-Dwelling Older Japanese2015

    • Author(s)
      Yu Taniguchi、Yoshinori Fujiwara、Mariko Nishi、Hiroshi Murayama、Yu Nofuji、Satoshi Seino、Rika Tajima、Yutaka Matsuyama、Shoji Shinkai.
    • Journal Title

      Journal of Epidemiology

      Volume: 25 Issue: 9 Pages: 592-599

    • DOI

      10.2188/jea.JE20140250

    • NAID

      130005096831

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Mini-Mental State Examinationにより評価した認知機能低下と将来の要介護発生との関連2015

    • Author(s)
      谷口優、藤原佳典、篠崎智大、天野秀紀、西真理子、村山洋史、野藤悠、清野諭、成田美紀、松尾恵理、横山友里、新開省二
    • Journal Title

      日本老年医学会雑誌

      Volume: 52 Pages: 86-93

    • NAID

      130004917195

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 地域在住高齢者における身体機能・骨格筋量・サルコペニアと認知機能との横断的・縦断的な関連性2015

    • Author(s)
      谷口優、清野諭、藤原佳典、野藤悠、西真理子、村山洋史、天野秀紀、松尾恵理、新開省二
    • Journal Title

      日本老年医学会雑誌

      Volume: 52 Pages: 269-277

    • NAID

      130005093073

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 脈波伝播速度の加齢変化パターンと死因別死亡に関する前向き研究2017

    • Author(s)
      谷口優、北村明彦、清野諭、村山洋史、野藤悠、横山友里、西真理子、天野秀紀、藤原佳典、新開省二
    • Organizer
      第59回日本老年医学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 大都市部の在宅都市部高齢者における犬または猫オーナーの身体・心理・社会的特徴2017

    • Author(s)
      谷口優、清野諭、田中泉澄、遠峰結衣、北村明彦、新開省二
    • Organizer
      第59回日本老年社会科学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Trajectory Pattern of Arterial Stiffness and Mortality Risk among Older Japanese2017

    • Author(s)
      Yu Taniguchi, Satoshi Seino, Hiroshi Murayama, Mariko Nishi, Hidenori Amano, Yoshinori Fujiwara, Akihiko Kitamura, Shoji Shinkai
    • Organizer
      21st IAGG World Congress of Gerontology and Geriatrics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prospective Study of Trajectories of Physical Performance and All-cause Mortality2017

    • Author(s)
      Yu Taniguchi, Hiroshi Murayama, Satoshi Seino, Mariko Nishi, Hidenori Amano, Yoshinori Fujiwara, Akihiko Kitamura, Shoji Shinkai
    • Organizer
      21st IAGG World Congress of Gerontology and Geriatrics symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高次生活機能の加齢変化パターンと医療費及び介護費との関連-草津町研究-2017

    • Author(s)
      谷口優、北村明彦、野藤悠、石崎達郎、清野諭、横山友里、村山洋史、光武誠吾、天野秀紀、西真理子、干川なつみ、濱口奈緒美、岡部たづる、藤原佳典、新開省二
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Glycosylated Hemoglobin Level and Subsequent Cognitive Decline Among Community-Dwelling Older Japanese.2016

    • Author(s)
      Yu Taniguchi, Akihiko Kitamura, Yoshinori Fujiwara, Mariko Nishi, Hidenori Amano,  Satoshi Seino, Yuri Yokoyama, Shoji Shinkai.
    • Organizer
      The Gerontological Society of America 68th Annual Scientific Meeting
    • Place of Presentation
      United States of America, New Orleans
    • Year and Date
      2016-11-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 群馬県草津町における介護予防14年間の成果(2)高齢住民の機能的健康度の推移.2016

    • Author(s)
      谷口優、北村明彦、横山友里、天野秀紀、清野諭、西真理子、野藤悠、村山洋史、岡部たづる、干川なつみ、藤原佳典、新開省二.
    • Organizer
      第75回日本公衆衛生学会総会
    • Place of Presentation
      グランフロント大阪(大阪府大阪市)
    • Year and Date
      2016-10-26
    • Related Report
      2016 Research-status Report
  • [Presentation] 身体機能の加齢変化パターンと余命に関する前向き研究.2016

    • Author(s)
      谷口優,清野諭,村山洋史,野藤悠,藤原佳典,西真理子,天野秀紀,新開省二.
    • Organizer
      第58回日本老年医学会学術集会
    • Place of Presentation
      石川県立音楽堂(石川県金沢市)
    • Year and Date
      2016-06-08
    • Related Report
      2016 Research-status Report
  • [Presentation] 長期縦断研究に基づく地域在宅高齢者の歩幅と認知機能低下との関連.2016

    • Author(s)
      谷口優
    • Organizer
      第5回日本ノルディック・ウォーク学会学術大会シンポジウム
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府吹田市)
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Trajectory Pattern of Grip Strength and Mortality Risk in a General Population of Older Japanese2015

    • Author(s)
      Yu Taniguchi, Shoji Shinkai, Mariko Nishi, Hiroshi Murayama, Hidenori Amano, Yu Nofuji, Satoshi Seino, Yoshinori Fujiwara
    • Organizer
      The Gerontological Society of America 67th Annual Scientific Meeting
    • Place of Presentation
      Orland(America)
    • Year and Date
      2015-11-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 認知症予防における身体活動・運動の意義‐疫学から実践まで‐2015

    • Author(s)
      谷口優
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 認知機能の加齢変化パターンと認知症発症に関する前向き研究2015

    • Author(s)
      谷口優,村山洋史,清野諭,野藤悠,松尾恵理,西真理子,天野秀紀,横山友里,成田美紀,藤原佳典,新開省二
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 身体機能の加齢変化パターンと余命に関する前向き研究2015

    • Author(s)
      谷口優,清野諭,村山洋史,野藤悠,藤原佳典,西真理子,天野秀紀,新開省二
    • Organizer
      第58回日本老年医学会学術集会
    • Place of Presentation
      石川県立音楽堂(石川県金沢市)
    • Year and Date
      2015-06-08
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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