| Project/Area Number |
15K17821
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
Murakami Kei 名古屋大学, トランスフォーマティブ生命分子研究所(WPI), 准教授 (90732058)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 芳香族アミノ化 / 銅触媒 / ルテニウム触媒 / スルホンイミド / 光触媒 / 窒素ラジカル / アミノ化 / 遷移金属触媒 / 二座配位子 |
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| Outline of Final Research Achievements |
Functional molecules such as natural products, pharmaceuticals, and organic materials are indispensable. Arylamines are one of the most important structures of these functional molecules. However, direct synthesis of arylamine through C-H functionalization of arenes is difficult. In this research, development of new synthesis of arylamines are studied. At the starting point, we elucidated the mechanism of copper-catalyzed arylamine (arylimide) synthesis by using DFT calculations. Based on this finding, we have developed a new arylamine (arylimide) synthesis using photocatalyst. The scope of the reaction is wide enough to cover various polyaromatic hydrocarbons as well as heteroarenes.
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