Project/Area Number |
15K17845
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Functional solid state chemistry
|
Research Institution | Yamaguchi University |
Principal Investigator |
Suzuki Yasutaka 山口大学, 大学院創成科学研究科, 准教授 (30634753)
|
Co-Investigator(Renkei-kenkyūsha) |
KAWAMATA JUN 山口大学, 大学院創生科学研究科, 教授 (40214689)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 多光子吸収 / 蛍光色素 / 発光生プローブ / 生体関連物質 / 非線形光学 / 多光子顕微鏡 / 発光性プローブ / 希土類金属錯体 / 生体イメージング / 多光子吸収現象 / 非線形光学材料 / 発光プローブ / 顕微鏡 |
Outline of Final Research Achievements |
In this study, I aimed to achieve 3 dimensional multi-photon multi-color imaging of biological material by using coordination complex. During the project, I clarified the appropriate ligand for designing metal complex probe for deep tissue imaging. By using metal complex equipped with appropriate ligand, 1030 nm excited multi-photon imaging was experimentally achieved. In addition, I tried to further functionalization of metal complex. As a result, oxygen concentration monitoring by using multi-photon excitation microscope was achieved in living cell.
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