| Project/Area Number |
15K18350
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology / General neuroscience
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| Research Institution | Kyoto University |
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Principal Investigator |
Ushimaru Mika 京都大学, 医学研究科, 特定研究員 (90604554)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 大脳皮質 / 徐波 / スピンドル波 / ガンマ波 |
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| Outline of Final Research Achievements |
Slow-wave oscillations, the predominant brain rhythm during sleep, are composed of Up/Down cycles. Depolarizing Up-states contain spindle and gamma components.
But it is unknown how diverse subtypes of neurons affect to gamma/spindle waves.
In this study, I recorded neural activity from cortical neuron subtypes (CCS, CPn and FS cells) from layer 5 and analyzed their relation to the gamma/spindle rhythms. I found that modulated cell ratio and firing phase in spindle/gamma oscillation were dependent on cell subtype and sublayer. These results suggest that firing activity of diverse neuron subtypes is highly associated with brain rhythms.
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