Research Project
Grant-in-Aid for Young Scientists (B)
Searching study for antimicrobial natural products were carried out to develop new leads of therapeutic agents for the treatment of ophthalmic infections. The study resulted in the isolation of new antimicrobial meroterpenes and acylphloroglucinols from Hypericaceous plants and new antimicrobial phenylcoumarins from a Calophyllaceous plant. Hypatulin A isolated from Hypericum patulum is a structurally interesting tricyclic meroterpene possessing antimicrobial activity.
All 2017 2016 2015 Other
All Journal Article (11 results) (of which Int'l Joint Research: 2 results, Peer Reviewed: 11 results, Acknowledgement Compliant: 8 results) Presentation (37 results) (of which Int'l Joint Research: 4 results) Remarks (2 results)
Tetrahedron Lett.
Volume: 58 Issue: 15 Pages: 1495-1498
10.1016/j.tetlet.2017.02.089
Volume: 58 Issue: 15 Pages: 1459-1461
10.1016/j.tetlet.2017.02.075
Org. Lett.
Volume: 18 Issue: 20 Pages: 5360-5363
10.1021/acs.orglett.6b02725
Volume: 18 Issue: 20 Pages: 5420-5423
10.1021/acs.orglett.6b02842
Fitoterapia
Volume: 114 Pages: 188-193
10.1016/j.fitote.2016.08.014
Volume: 57 Issue: 29 Pages: 3175-3178
10.1016/j.tetlet.2016.06.028
J. Nat. Med.
Volume: 70 Issue: 4 Pages: 780-788
10.1007/s11418-016-1015-z
40020934124
Chemical and Pharmaceutical Bulletin
Volume: 64 Issue: 7 Pages: 991-995
10.1248/cpb.c16-00243
130005160022
Volume: 64 Issue: 7 Pages: 924-929
10.1248/cpb.c16-00146
130005160077
Volume: 64 Issue: 7 Pages: 691-694
10.1248/cpb.c16-00245
130005160021
Volume: 56 Issue: 30 Pages: 4502-4504
10.1016/j.tetlet.2015.05.114
http://www.tokushima-u.ac.jp/ph/faculty/labo/cgn
http://www.tokushima-u.ac.jp/ph/faculty/labo/cgn/publication.html