| Project/Area Number |
15K18913
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental and hygienic pharmacy
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 危険ドラッグ / プロテオミクス / バイオマーカー / 薬物依存性バイオマーカー |
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| Outline of Final Research Achievements |
In this research, it aims to establish the novel rapid and handy measurement system for designer drug abuse in vitro. Differential proteome analysis was performed to distinguish between phenethylamines, cathinones, tryptamine and cannabinoids treated human neuronal cell models. As a result, we identified latexin(LXN) protein as a candidate of drug abuse biomarker. Furthermore, we established LXN measurement system in vitro.
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