Analysis of Japanese encephalitis virus infection in mosquito cells
Project/Area Number |
15K19084
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Parasitology (including sanitary zoology)
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Research Institution | Yamaguchi University |
Principal Investigator |
KUWATA Ryusei 山口大学, 共同獣医学部, 学術研究員 (00711219)
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Research Collaborator |
MAEDA Ken 山口大学, 共同獣医学部, 教授 (90284273)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 節足動物媒介感染症 / 蚊 / ウイルス / 細胞 / 受容体 / 感染症 / 日本脳炎ウイルス / フラビウイルス / アルボウイルス / 人獣共通感染症 / 衛生動物学 / ウイルス学 |
Outline of Final Research Achievements |
Japanese encephalitis virus (JEV) causes viral encephalitis in Asia, estimating nearly 68000 clinical cases of JE globally each year. JEV is transmitted by mosquitoes, and maintained in a cycle between mosquitoes and vertebrate hosts, such as pigs and birds, in nature. Some of JEV receptor on cell surface has been reported on vertebrate cells, but a little or none on mosquito cells. We have established a new experimental systems to examine the cell factor binding to JEV by using virus-like particles (VLPs). Now we applied the JEV_VLPs systems to elucidate the mechanisms for the JEV infections on mosquito cells.
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Report
(4 results)
Research Products
(49 results)
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[Journal Article] Getah virus epizootic among wild boars in Japan around 20122018
Author(s)
Kuwata R, Shimoda H, Phichitraslip T, Prasertsincharoen N, Noguchi K, Yonemitsu K, Minami M, Supriyono, Tran NTB, Takano A, Suzuki K, Nemoto M, Bannai H, Yokoyama M, Takeda T, Jittapalapong S, Rerkamnuaychoke W, Maeda K.
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Journal Title
Archives of Virology
Volume: 印刷中
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Characterization of a novel thogotovirus isolated from Amblyomma testudinarium ticks in Ehime, Japan: A significant phylogenetic relationship to Bourbon virus.2018
Author(s)
Ejiri H, Lim CK, Isawa H, Fujita R, Murota K, Sato T, Kobayashi D, Kan M, Hattori M, Kimura T, Yamaguchi Y, Takayama-Ito M, Horiya M, Posadas-Herrera G, Minami S, Kuwata R, Shimoda H, Maeda K, Katayama Y, Mizutani T, Saijo M, Kaku K, Shinomiya H, Sawabe K
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Journal Title
Virus Research
Volume: 249
Pages: 57-65
Related Report
Peer Reviewed / Open Access
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[Journal Article] Isolation and characterization of Kabuto Mountain virus, a new tick-borne phlebovirus from Haemaphysalis flava ticks in Japan2018
Author(s)
Ejiri H, Lim CK, Isawa H, Yamaguchi Y, Fujita R, Takayama-Ito M, Kuwata R, Kobayashi D, Horiya M, Posadas-Herrera G, Iizuka-Shiota I, Kakiuchi S, Katayama Y, Hayashi T, Sasaki T, Kobayashi M, Morikawa S, Maeda K, Mizutani T, Kaku K, Saijo M, Sawabe K
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Journal Title
Virus Research
Volume: 244
Pages: 252-261
Related Report
Peer Reviewed / Open Access
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[Journal Article] Isolation and characterization of Tarumizu tick virus: A new coltivirus from Haemaphysalis flava ticks in Japan2018
Author(s)
Fujita R, Ejiri H, Lim CK, Noda S, Yamauchi T, Watanabe M, Kobayashi D, Takayama-Ito M, Murota K, Posadas-Herrera G, Minami S, Kuwata R, Yamaguchi Y, Horiya M, Katayama Y, Shimoda H, Saijo M, Maeda K, Mizutani T, Isawa H, Sawabe K
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Journal Title
Virus Research
Volume: 242
Pages: 131-140
Related Report
Peer Reviewed / Open Access
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[Journal Article] The genetic diversity of D-loop sequences in eastern bent-winged bats (<i>Miniopterus fuliginosus</i>) living in Wakayama Prefecture, Japan2017
Author(s)
Iida K, Kobayashi R, Hengjan Y, Nagata N, Yonemitsu K, Nunome M, Kuwata R, Suzuki K, Ichiyanagi K, Maeda K, Ohmori Y, Hodo E
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Journal Title
Journal of Veterinary Medical Science
Volume: 79
Issue: 6
Pages: 1142-1145
DOI
NAID
ISSN
0916-7250, 1347-7439
Related Report
Peer Reviewed / Open Access
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[Journal Article] Influenza A virus infection in Japanese wild boars (<i>Sus scrofa leucomystax</i>)2017
Author(s)
Shimoda H, Nguyen DV, Yonemitsu K, Minami S, Nagata N, Hara N, Kuwata R, Murakami S, Kodera Y, Takeda T, Yoshikawa Y, Horimoto T, Maeda K.
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Journal Title
Journal of Veterinary Medical Science
Volume: 79
Issue: 5
Pages: 848-851
DOI
NAID
ISSN
0916-7250, 1347-7439
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Isolation and phylogenetic analysis of canine distemper virus among domestic dogs in Vietnam2017
Author(s)
Nguyen DV, Suzuki J, Minami S, Yonemitsu K, Nagata N, Kuwata R, Shimoda H, Vu CK, Truong TQ, Maeda K
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Journal Title
Journal of Veterinary Medical Science
Volume: 79
Issue: 1
Pages: 123-127
DOI
NAID
ISSN
0916-7250, 1347-7439
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Simple and specific method for detection of antibodies against hepatitis E virus in mammalian species2016
Author(s)
Yonemitsu K, Terada Y, Kuwata R, Nguyen DV, Shiranaga N, Tono S, Matsukane T, Yokoyama M, Suzuki K, Shimoda H, Takano A, Muto M, Maeda K
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Journal Title
Journal of Virological Methods
Volume: 238
Pages: 56-61
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Genetic and biological characterization of Muko virus, a new distinct member of the species Great Island virus (genus Orbivirus, family Reoviridae), isolated from ixodid ticks in Japan.2015
Author(s)
Ejiri H, Lim CK, Isawa H, Kuwata R, Kobayashi D, Yamaguchi Y, Ito M, Kinoshita H, Kakiuchi S, Horiya M, Kotaki A, Takasaki T, Madeda K, Hayashi T, Sasaki T, Kobayashi M, Saijo M, Sawabe K
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Journal Title
Archives of Virology
Volume: 160
Pages: 2965-2977
Related Report
Peer Reviewed / Open Access
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[Journal Article] Isolation and characterization of a novel Rhabdovirus from a wild boar (Sus scrofa) in Japan.2015
Author(s)
Sakai K, Hagiwara K, Omatsu T, Hamasaki C, Kuwata R, Shimoda H, Suzuki K, Endoh D, Nagata N, Nagai M, Katayama Y, Oba M, Kurane I, Saijo M, Morikawa S, Mizutani T, Maeda K.
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Journal Title
Veterinary Microbiology
Volume: 179
Pages: 197-203
Related Report
Peer Reviewed / Open Access
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[Presentation] A recent Getah virus outbreak in Japan was occurred during 20122017
Author(s)
Kuwata R, Shimoda H, Bannai H, Nemoto M, Phichitraslip T, Prasertsincharoen N, Supriyono, Minami S, Nagata N, Yonemitsu K, Noguchi K, Takano A, Jittapalapong S, Rerkamnuaychoke W, Maeda K
Organizer
The 65th Annual Meeting of the Japanese Society for Virology
Related Report
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[Presentation] Analysis of the endogenous virus-like sequences in mosquito genome2017
Author(s)
Torii S, Kuwata R, Supriyono, Noguchi K, Nagata N, Minami S, Yonemitsu K, Shimoda H, Kesumawati U, Itokawa K, Isawa H, Sawabe K, Maeda K
Organizer
The 65th Annual Meeting of the Japanese Society for Virology
Related Report
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[Presentation] Detection and isolation of tick-borne bacteria (Rickettsia spp., Anaplasma spp., Ehrlichia spp. and Borrelia spp.) in Aponomma lucasi ticks collected from Lizard (Varanus salvator) in Indonesia2017
Author(s)
Supriyono, Takano A, Kuwata R, Shimoda H, Torii S, Minami S, Nagata N, Yonemitsu K, Phichitraslip T, Prasertsincharoen N, Dargantes AP, Abella JA, Baltazar ET, Simborio LT, Panpiansil J, Rerkamnuaychoke W, Ebihara H, Hadi UK, Setiyono A, Agungpriyono S, Hondo E, Maeda K.
Organizer
第160回日本獣医学会学術集会
Related Report
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[Presentation] Surveillance for mosquito-borne infectious diseases in Asian countries2016
Author(s)
Kuwata R, Supriyono, Kesumawati U, Sugiyama H, Torii S, Minami S, Nagata N, Yonemitsu K, Dung VN, Shimoda H, et al.
Organizer
International Young Scientists’ Symposium in Bogor Agricultural University ‘Fusion of Science to Strengthen Young Scientist Capacity in Achieving the Global Health’
Place of Presentation
ボゴール農科大学(ボゴール・インドネシア)
Year and Date
2016-11-29
Related Report
Int'l Joint Research
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[Presentation] 東南アジア諸国における蚊保有ウイルスの調査2016
Author(s)
鍬田龍星,杉山弘樹,鳥井駿,高野愛,下田宙,米満研三,小林良祐,Hengjan Y, Phichitraslip T, Prasertsincharoen N, Spriyono, Kesumawati U, Setiyono A, Dargantes AP, Abella JA, Baltazar ET, Simborio LT, Panpiansil J, Agungpriyono S, Rerkamnuaychoke W, 海老原秀喜,本道栄一,前田健
Organizer
第23回トガ・フラビ・ペスチウイルス研究会
Place of Presentation
北海道大学(北海道札幌市)
Year and Date
2016-10-22
Related Report
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[Presentation] 日本脳炎媒介蚊の吸血活動と遺伝子診断について2016
Author(s)
鍬田龍星、杉山弘樹、米満健三、Simborio LT, Baltazar ET, Abella JA, Dargantes AP, Kesumawati U, Setiyono A, Rerkamnuaychoke W, Prasertsincharoen N, 下田宙、本道栄一、前田健
Organizer
第51回日本脳炎ウイルス生態学研究会
Place of Presentation
リステル猪苗代(福島県那麻郡猪苗代町)
Year and Date
2016-05-13
Related Report
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