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Toward the establishment of more suitable strain of Lucilia sericata for maggot debridement therapy.

Research Project

Project/Area Number 15K19088
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Parasitology (including sanitary zoology)
Research InstitutionJikei University School of Medicine

Principal Investigator

Aonuma Hiroka  東京慈恵会医科大学, 医学部, 助教 (60451457)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords創傷治癒 / マゴットセラピー / ヒロズキンバエ / 衛生動物
Outline of Final Research Achievements

Maggot debridement therapy (MDT) is one of biotherapy that involves the application of green bottle fly, Lucilia sericata, larvae (Maggot) to the necrotic wounds. Maggot application to the wound promotes removal of necrotic tissues, disinfection, and healing. Toward the establishment of more suitable strain of fly for MDT, a measure to evaluate the ability of maggot for debridement has been developed. Controlling maggot pupation by reducing acdysteroids was also examined, which could be lead to the extension of days between each treatment. Establishment of more suitable maggot strain could potentially improve therapeutic effect and patient outcome with MDT.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2016 2015

All Presentation (7 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] ヒト組織を用いたマゴットセラピー評価系の構築2016

    • Author(s)
      吉田拓磨・青沼宏佳・宮脇剛司・嘉糠洋陸
    • Organizer
      第4回 日本マゴットセラピー症例検討会
    • Place of Presentation
      京都大学(京都府京都市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] 創傷治療に用いる医療用ウジの改良に向けた試み2016

    • Author(s)
      吉田拓磨・青沼宏佳・宮脇剛司・嘉糠洋陸
    • Organizer
      第8回 創傷外科学会総会・学術集会
    • Place of Presentation
      ホテルメトロポリタン東京池袋(東京都豊島区)
    • Year and Date
      2016-07-21
    • Related Report
      2016 Annual Research Report
  • [Presentation] マゴットセラピーに用いるヒロズキンバエ(Lucilia sericata)幼虫の改良に向けた試み2016

    • Author(s)
      吉田拓磨・青沼宏佳・宮脇剛司・嘉糠洋陸
    • Organizer
      第68回 日本衛生動物学会大会
    • Place of Presentation
      栃木県総合文化センター(栃木県宇都宮市)
    • Year and Date
      2016-04-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] マゴットセラピーに用いる医療用ウジの改良に向けた試み2016

    • Author(s)
      吉田拓磨・青沼宏佳・宮脇剛司・嘉糠洋陸
    • Organizer
      第59回 日本形成外科学会総会・学術集会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-04-15
    • Related Report
      2016 Annual Research Report
  • [Presentation] Artificial control of development of Lucilia sericata larvae in maggot debridement therapy2015

    • Author(s)
      Takuma Yoshida, Hiroka Aonuma, Takeshi Miyawaki, Hirotaka Kanuka
    • Organizer
      International Wound & Biotherapy Conference 2015
    • Place of Presentation
      マレーシア
    • Year and Date
      2015-10-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] マゴットセラピーの国外事情2015

    • Author(s)
      吉田拓磨・青沼宏佳・宮脇剛司・嘉糠洋陸
    • Organizer
      第3回 日本マゴットセラピー症例検討会
    • Place of Presentation
      岡山
    • Year and Date
      2015-10-03
    • Related Report
      2015 Research-status Report
  • [Presentation] 創傷治療における医療用ウジの改良に向けた試み2015

    • Author(s)
      吉田拓磨・青沼宏佳・岡戸清・宮脇剛司・内田満・嘉糠洋陸
    • Organizer
      第7回日本創傷外科学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-24
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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