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Flexible bronchoscopy under sedation in older patients

Research Project

Project/Area Number 15K19282
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field General internal medicine(including psychosomatic medicine)
Research InstitutionNagoya University

Principal Investigator

Okachi Shotaro  名古屋大学, 医学部附属病院, 病院助教 (30742407)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Keywords高齢者 / 気管支鏡 / 鎮静 / 肺癌 / ミダゾラム / 鎮静剤
Outline of Final Research Achievements

Respiratory diseases such as lung cancer are a disease that is likely to occur in the elderly, and bronchoscopy is often required for diagnosis. There are adverse events in bronchoscopy and sedation to relieve pain, especially concerning elderly people. We examined the safety and usefulness of bronchoscopy under sedation using midazolam in the elderly during the research period and examined appropriate sedation method. We administered adjusted dose of midazolam according to age and body weight. As a result, comparison was made between elderly people aged 80 years or over and those aged 79 years or younger, no obvious difference in diagnostic rate and complication rate of bronchoscopy was observed. We demonstrated the safety and efficacy of bronchoscopy under sedation with midazolam even in elderly patients.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 2015

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 3 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] Safety and efficacy of diagnostic flexible bronchoscopy in very old patients with lung cancer2018

    • Author(s)
      Okachi Shotaro、Imaizumi Kazuyoshi、Imai Naoyuki、Shimizu Takahiro、Hase Tetsunari、Morise Masahiro、Hashimoto Naozumi、Sato Mitsuo、Hasegawa Yoshinori
    • Journal Title

      European Geriatric Medicine

      Volume: 9 Issue: 2 Pages: 255-262

    • DOI

      10.1007/s41999-018-0033-7

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Factors Affecting the Diagnostic Yield of Transbronchial Biopsy Using Endobronchial Ultrasonography with a Guide Sheath in Peripheral Lung Cancer2016

    • Author(s)
      Shotaro Okachi, Naoyuki Imai, Kazuyoshi Imaizumi, Shingo Iwano, Masahiko Ando, Tetsunari Hase, Hiromichi Aso, Masahiro Morise, Keiko Wakahara, Satoru Ito, Naozumi Hashimoto, Mitsuo Sato, Masashi Kondo, and Yoshinori Hasegawa
    • Journal Title

      Internal Medicine

      Volume: 55 Issue: 13 Pages: 1705-1712

    • DOI

      10.2169/internalmedicine.55.6341

    • NAID

      130005161019

    • ISSN
      0918-2918, 1349-7235
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical impact of the lower limit of normal of FEV1/FVC on survival in lung cancer patients undergoing thoracic surgery2016

    • Author(s)
      Asuka Matsuzaki, Naozumi Hashimoto, Shotaro Okachi, Tetsuo Taniguchi, Koji Kawaguchi, Takayuki Fukui , Kenji Wakai, Kohei Yokoi, Yoshinori Hasegawa
    • Journal Title

      Respiratory Investigation

      Volume: 印刷中 Issue: 3 Pages: 184-192

    • DOI

      10.1016/j.resinv.2015.11.006

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Factors Affecting the Diagnostic Yield of Transbronchial Biopsy Using Endobronchial Ultrasonography with a Guide Sheath in Peripheral Lung Cancer2016

    • Author(s)
      Shotaro Okachi,Naoyuki Imai, Kazuyoshi Imaizumi, Shingo Iwano, Masahiko Ando, Tetsunari Hase, Hiromichi Aso, Masahiro Morise, Keiko Wakahara, Satoru Ito, Naozumi Hashimoto, Mitsuo Sato, Masashi Kondo, Yoshinori Hasegawa
    • Journal Title

      Internal Medicine

      Volume: 印刷中

    • NAID

      130005161019

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Massive mediastinal cryptococcosis in a young immunocompetent patient.2015

    • Author(s)
      Okachi S, Wakahara K, Kato D, Umeyama T, Yagi T, Hasegawa Y.
    • Journal Title

      Respirol Case Rep.

      Volume: 3 Issue: 3 Pages: 95-98

    • DOI

      10.1002/rcr2.111

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 気管支鏡で直視所見を有する症例に対するガイドシース併用気管支腔内超音波断層法(EBUS-GS)併用気管支内生検の有用性と安全性2015

    • Author(s)
      伊藤 亮太, 今井 直幸, 高嶋浩司, 與語 直之, 岡地祥太郎, 青山大輔, 犬飼朗博, 安藤昌彦, 今泉和良, 長谷川 好規
    • Journal Title

      気管支学

      Volume: 37 Pages: 375-381

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] 肺癌診断目的に実施した気管支鏡後の呼吸器感染症合併についての検討2017

    • Author(s)
      岡地祥太郎,長谷川好規
    • Organizer
      第54回呼吸器内視鏡学会地方会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 80歳以上の高齢者に対する気管支鏡2016

    • Author(s)
      岡地祥太郎,長谷晢成,麻生裕紀,森瀬昌宏,若原恵子,橋本直純,佐藤光夫,近藤征史,長谷川好規
    • Organizer
      第39回日本呼吸器内視鏡学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 末梢小型肺癌に対するEBUS-GSの診断能とその予測因子に関する検討2015

    • Author(s)
      岡地祥太郎, 今井直之、今泉和良、岩野信吾, 安藤昌彦,、長谷哲成、麻生裕紀、森瀬昌宏、若原恵子、橋本直純、佐藤光夫、近藤征史、長谷川 好規
    • Organizer
      第38回日本呼吸器内視鏡学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-06-11
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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