| Project/Area Number |
15K20148
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | The University of Tokushima |
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Principal Investigator |
ABE Akiko 徳島大学, 大学院医歯薬学研究部(医学系), 助教 (30748588)
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| Research Collaborator |
IMOTO Issei
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 卵巣癌 / 遺伝性腫瘍 / 遺伝子パネル検査 / HBOC / BRCA |
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| Outline of Final Research Achievements |
We investigated the awareness survey and the rate of 11 genes including gBRCA1/2 mutation with ovarian cancer. After genetic counselling, 124 of 127 patients with ovarian cancer consented of analysis. For 108 patients, analyses for gBRCA1/2 test were performed. 80% wished for gBRCA1/2 result disclosure, and germline gene mutation was identified in 15.7%. Almost patients with ovarian cancer patients wanted to know genetic risk after genetic counselling. We are planning to develop a surveillance system that includes relatives.
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