Change of somatosensory function of the tongue caused by chorda tympani nerve disorder and activation of MAP kinase in Geniculate ganglion neurons after middle ear surgery
Project/Area Number |
15K20235
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Otorhinolaryngology
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Research Institution | Hyogo Medical University |
Principal Investigator |
|
Research Collaborator |
MAEDA EMI
TATUMI EMIKO
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Project Period (FY) |
2015-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 鼓索神経 / 三叉神経 / 舌知覚異常 / アブミ骨手術 / 舌知覚障害 / 中耳手術 / 味覚障害 |
Outline of Final Research Achievements |
The CTN was gently touched or stretched in all patients. Postoperative thresholds on the operated side were significantly higher than preoperative thresholds in all tests in the patients who underwent all 3 kinds of tests. Tongue somatosensory symptoms improved significantly earlier than the taste disturbance postoperatively, and the sensory thresholds returned to the baseline along with recovery of symptoms. These findings suggest that dysfunction of the chorda tympani nerve (CTN) occurred following surgery even when the CTN was preserved, and that the sensory nerve threshold of the tongue correlated with the symptom of lingual numbness. The CTN may play a role not only in taste function, but also in the somatosensory function of the tongue.
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Report
(3 results)
Research Products
(3 results)