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Nobel surface treatment for better implant-ECM interface

Research Project

Project/Area Number 15K20445
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthodontics/ Dental materials science and
Research InstitutionKyushu University

Principal Investigator

Furuhashi Akihiro  九州大学, 大学病院, 医員 (60608975)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords細胞外マトリックス / 細胞外基質 / 歯科インプラント
Outline of Final Research Achievements

The cell adhesion is divided into two types; cell-cell contact and cell-extracellular matrix (ECM) contact. Dental implants are one of the ECM environments for the surrounding cells. In this study, cell-cell contact and cell-ECM contact are evaluated. Cells were seeded onto various kinds of coated dishes. And 3 dimensional (3D) cultures were also performed. Cells showed different adhesion pattern onto various coating. When cultured in 3-D condition, the cells showed 3-D branching-like morphology.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (12 results)

All 2017 2016 2015 2014 Other

All Int'l Joint Research (1 results) Journal Article (5 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 5 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (6 results) (of which Int'l Joint Research: 3 results)

  • [Int'l Joint Research] ペンシルバニア大学(米国)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Soft tissue sealing around dental implants based on histological interpretation2016

    • Author(s)
      Atsuta I, Ayukawa Y, Kondo R, Matsuura Y, Ohshiro W, Furuhashi A, Tsukiyama Y, Koyano K.
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 60 Issue: 1 Pages: 3-11

    • DOI

      10.1016/j.jpor.2015.07.001

    • NAID

      130007936706

    • ISSN
      1883-1958, 1883-9207
    • Year and Date
      2016-01-25
    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neural Progenitor-Like Cells Induced From Human Gingiva-Derived Mesenchymal Stem Cells Regulate Myelination of Schwann Cells in Rat Sciatic Nerve Regeneration2016

    • Author(s)
      Zhang Q, Nguyen P, Xu Q, Park W, Lee S, Furuhashi A, Le A
    • Journal Title

      stem cell translational medicine

      Volume: 5 Issue: 2 Pages: 1-13

    • DOI

      10.5966/sctm.2016-0177

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of CaCl2 hydrothermal treatment of titanium implant surfaces on early epithelial sealing2015

    • Author(s)
      Oshiro W. Ayukawa Y, Atsuta I, Furuhashi A, Yamazoe J, Kondo R, Sakaguchi M, Matsuura Y, Tsukiyama Y, Koyano K.
    • Journal Title

      Colloids and Surfaces B Biointerphases

      Volume: 未定 Pages: 141-147

    • DOI

      10.1016/j.colsurfb.2015.04.025

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Acceleration of hard and soft tissue healing in the oral cavity by a single transmucosal injection of fluvastatin-impregnated poly (lactic-co-glycolic acid) microspheres. An in vitro and rodent in vivo study2015

    • Author(s)
      Yasunami N, Ayukawa Y, Furuhashi A, Atsuta I, Rakhmatia YD, Moriyama Y, Masuzaki T, Koyano K
    • Journal Title

      Biomed Mater

      Volume: 11 Issue: 1 Pages: 015011-015011

    • DOI

      10.1088/1748-6041/11/1/015001

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Fibroblast attachment onto novel titanium mesh membranes for guided bone regeneration2014

    • Author(s)
      Rakhmatia YD, Ayukawa Y, Atsuta I, Furuhashi A, Koyano K
    • Journal Title

      Odontology

      Volume: - Issue: 2 Pages: 2180226-2180226

    • DOI

      10.1007/s10266-014-0151-8

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Effect of Ca-HT Treatment of Titanium on Adhesion Properties2017

    • Author(s)
      Takuya Haraguchi, Yasunori Ayukawa, Akihiro Furuhashi, Ikiru Atsuta, Yoichiro Ogino, Wakana Oshiro, Noriyuki Yasunami, Kiyoshi Koyano
    • Organizer
      95th General Session of the International Association for Dental Research
    • Place of Presentation
      Moscone Center, CA
    • Year and Date
      2017-03-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] INDUCED NEURAL PROGENITOR-LIKE CELLS FROM HUMAN GINGIVA-DERIVED MESENCHYMAL STEM CELLS REGULATE MYELINATION OF SCHWANN CELLS IN RAT SCIATIC NERVE REGENERATION2017

    • Author(s)
      Zhang Q, Nguyen P, Xu Q, Park W, Lee S, Furuhashi A, Le A
    • Organizer
      American Cleft Palate-Craniofacial association 74th annual meeting
    • Place of Presentation
      Broadmoor in Colorado Springs, CO
    • Year and Date
      2017-03-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] チタンの塩化カルシウム水熱処理がタンパク質,細胞および細菌の付着に与える影響2016

    • Author(s)
      原口拓也,鮎川保則,荻野洋一郎,熱田生,安波礼之,古橋明大,大城和可奈,古谷野潔
    • Organizer
      第46回公益社法人日本口腔インプラント学会学術大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] ジルコニア製インプラントにおける軟組織封鎖性の検討2016

    • Author(s)
      熱田生,鮎川保則,古橋明大,成松生枝,古谷野潔
    • Organizer
      日本歯科理工学会九州地方会夏期セミナー
    • Place of Presentation
      北九州市
    • Year and Date
      2016-08-18
    • Related Report
      2016 Annual Research Report
  • [Presentation] Potential Application of Human Adult Stem Cells from the Dental Follicle Tissues for Salivary Gland Regeneration2016

    • Author(s)
      Xu Q#, Furuhashi A#, Zhang Q, Jiang C, Le A.※. # Both authors contribute equally to this study
    • Organizer
      Penn Dental Medicine Research Day
    • Place of Presentation
      University of Pennsylvania, PA
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] PLGA-フルバスタチン複合体局所単回投与による抜歯窩及びインプラント周囲組織に対する治癒促進効果の検討2015

    • Author(s)
      安波礼之, 鮎川保則, 古橋明大, 熱田生, 古谷野潔
    • Organizer
      第45回公益社団法人日本口腔インプラント学会学術大会
    • Place of Presentation
      岡山
    • Year and Date
      2015-09-21
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2022-02-16  

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