An establising novel antibody for GDD1/TMEM16E/ANO5

Research Project

Project/Area Number	15K20533
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Surgical dentistry
Research Institution	Hiroshima University
Principal Investigator	Kubozono Kazumi 広島大学, 病院(歯), 歯科診療医 (80750132)
Project Period (FY)	2015-04-01 – 2017-03-31
Project Status	Completed (Fiscal Year 2016)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	TMEM16E / ANO5 / LGMD2L / GDD / GDD1 / anoctamin5 / lgmd2l / Anoctamin 5
Outline of Final Research Achievements	Development of application-specific antibodies for TMEM16E will provide great advances in TMEM16E-related diseases understanding. In this DNA-immunization method project, application(eg, Western blotting, immunocytochemistry and flowcytometry)-specific high affinity monoclonal antibodies were established, which will provide further understanding of disease-related TMEM16E in mice tissues.

Report

(3 results)