| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
In this study, to clarify the relationship between the pathology of cognitive dysfunction and the change of saliva components in dementia patients, we aimed to develop a new diagnostic and evaluation method of cognitive dysfunction using saliva by metabolome analysis. We conducted experiments on animals and human subjects, and revealed the changes in saliva components by cognitive dysfunction using metabolome analysis. These findings indicate relation to saliva component and cognitive function, and it was possible to study of saliva test.
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