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Study on Quality of life and physical activity of patients who received antiviral therapy for chronic hepatitis C

Research Project

Project/Area Number 15K20703
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Clinical nursing
Research InstitutionSaga University

Principal Investigator

Kawakubo Megumi  佐賀大学, 医学部, 助教 (90710252)

Project Period (FY) 2015-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords慢性肝炎 / C型肝炎 / HRQOL / DAA治療 / 身体活動量 / 抗ウイルス治療 / 肝炎治療 / DAAs / QOL / 抗ウイルス療法 / QOL / 臨床看護
Outline of Final Research Achievements

This study is longitudinal study that surveyed health-related quality of life (HRQOL) and physical activity in patients who received antiviral therapy for chronic hepatitis C since starting treatment to two years after finishing treatment.
We analyzed HRQOL in 34 of the 107 who returned questionnaire at all survey points and not applicable with exclusion criteria.HRQOL didn’t change between the start of treatment and 2 years after the end of treatment.Physical activity didn’t change between the start of treatment and the end of treatment, and it cleared that constant physical activity could be maintained during the treatment.

Academic Significance and Societal Importance of the Research Achievements

本研究結果は、近年普及するC型肝炎に対するDAA(Directed-acting activiral)治療が、患者のQOLや生活行動への影響が少ないことを示した。治療と仕事の両立の実現可能性を強調する結果であり、未治療群の受療促進にあたっての有用な根拠資料となり得る。

Report

(6 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2019 2018 2016 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Chronic Hepatitis C Treatment with Daclatasvir Plus Asunaprevir Does Not Lead to a Decreased Quality of Life2018

    • Author(s)
      Megumi Kawakubo, Yuichiro Eguchi, Michiaki Okada, Shinji Iwane, Satoshi Oeda, Taiga Otsuka, Syunya Nakashita, Norimasa Araki, Akemi Koga
    • Journal Title

      Internal Medicine

      Volume: -

    • NAID

      130007404858

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] C型慢性肝炎に対する経口剤治療を受けた患者の治療前から治療終了後2年のHRQOLの変化2019

    • Author(s)
      川久保愛、古賀明美
    • Organizer
      第13回日本慢性看護学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Direct antiviral agents for Chronic Hepatitis C Maintains Quality of Life evaluated by patient-reported Questionnaire2016

    • Author(s)
      Kawakubo M, Koga A, Okada M, Eguchi Y
    • Organizer
      Asian Pacific Digestive Week(APDW 2016)
    • Place of Presentation
      Kobe Convention Center
    • Year and Date
      2016-11-02
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] C型慢性肝炎に対する経口剤治療を受ける患者の治療前から治療開始後12週の身体活動量とQOLの変化2015

    • Author(s)
      川久保愛、古賀明美
    • Organizer
      第35回日本看護科学学会学術集会
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2015-12-05
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2022-11-04  

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