| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Outline of Final Research Achievements |
In the eukaryotic cells, complex membrane dynamics systems are constructed for the transport of various substances between inside and outside the cells. This membrane dynamics is involved not only in the transport of substances but also in the control of signal transduction from outside the cell. Rab7 protein is one of factors that regulates the intracellular membrane dynamics. As a result of analyzing using Rab7 gene-deficient mice, disruption of the Rab7 gene causes signaling defect of cell proliferation and differentiation at the developmental stage and embryogenesis stops.
|
