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Molecular morphological study on the effect of low nutrition in fetal stage on the digestive tract after birth

Research Project

Project/Area Number 15K21558
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits
Applied health science
Research InstitutionNakamura Gakuen College

Principal Investigator

KUMAGAI Nana  中村学園大学, 栄養科学部, 助教 (70552983)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords低栄養 / 妊娠 / 経産婦 / 胎児 / 新生児 / 乳児 / 消化管 / 分子形態学 / 胎児期 / 新生児期 / 乳飲期 / 小腸 / 大腸 / 妊娠初期 / 腎臓 / 妊娠中期
Outline of Final Research Achievements

I observed Molecular morphologically using the digestive tract (small intestine and large intestine) of neonates born from Wistar female rats, which are proper pregnancy or pregnant under low nutrition at different times. Shorter villi were observed in the ileum of neonates born from pregnancy mothers under low nutrition (low nutritional group) than the neonates born from normal pregnancy mothers (control・normal group).
In the large intestine, proximal colon of the low nutritional group, there are some difference from the control group. In addition, differences were found depending on the timing of low nutrition during pregnancy, there are suggested that low nutrition during pregnancy effects the small intestine and large intestine of children after birth

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2017 2016 2015

All Presentation (4 results)

  • [Presentation] 妊娠中の低栄養が出生後の児の栄養補給系(小腸)に及ぼす影響に関する三次元的解析2017

    • Author(s)
      熊谷奈々、三成由美、藤田 守
    • Organizer
      第64回日本栄養改善学会全国学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 栄養補給法の違いが新生児(仔)空腸吸収上皮細胞の吸収機構に及ぼす影響に関する超微形態学的・免疫組織化学的研究2016

    • Author(s)
      熊谷奈々、馬場良子、三成由美、徳井教孝、藤田 守
    • Organizer
      第4回日本栄養改善学会九州・沖縄支部学術総会
    • Place of Presentation
      中村学園大学
    • Year and Date
      2016-09-17
    • Related Report
      2016 Research-status Report
  • [Presentation] 妊娠中の低栄養は出生後の栄養補給系(小腸)に影響を及ぼす2015

    • Author(s)
      熊谷奈々、馬場良子、三成由美、藤田 守
    • Organizer
      第62回日本栄養改善学会学術集会
    • Place of Presentation
      福岡国際会議場、福岡サンパレスホテル
    • Year and Date
      2015-09-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 胎内低栄養環境における消化管のエピゲノム変化2015

    • Author(s)
      藤田 守、熊谷奈々、馬場良子、森本景之、小林道也、中村桂一郎
    • Organizer
      第47回日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      長崎大学 医学部 良順会館、ポンぺ会館
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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