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Electron beam excitation assisted microscopy for fine bubble observation

Research Project

Project/Area Number 16H03883
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Optical engineering, Photon science
Research InstitutionShizuoka University

Principal Investigator

Kawata Yoshimasa  静岡大学, 電子工学研究所, 教授 (70221900)

Co-Investigator(Kenkyū-buntansha) 居波 渉  静岡大学, 電子工学研究所, 教授 (30542815)
真田 俊之  静岡大学, 工学部, 准教授 (50403978)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2018: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2016: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Keywordsファインバブル / 光学顕微鏡 / 電子顕微鏡 / 超解像 / 流体解析 / 光計測 / 超解像顕微鏡 / ファイバブル / ソフトマテリアル / ナノ計測 / 光散乱計測 / ナノテクノロジー / カソードルミネッセンス
Outline of Final Research Achievements

We have developed electron beam excitation assisted microscope for observation of fine bubbles. Fine bubbles are expected to open new applications such as analyses of colloidal solution, bio-materials, soft materials, because they have larger surface area and larger charge on the surfaces. We excited plasma emission by irradiating focused electron beam directly to bubbles, and imaged the bubbles with high resolution. The higher resolution than the optical microscope was demonstrated.

Academic Significance and Societal Importance of the Research Achievements

本研究では、液中におけるマイクローナノスケールのファインバブルを高分解能かつ高感度に観察する電子線励起発光顕微鏡を開発し、さまざまな応用分野へ展開することを目的として、基礎解析およびシステム開発を行なってきた。開発した電子線励起超解像顕微鏡を用いて、水中に浮遊するファインバブルおよび内部にアルゴンガスを含むファインバブルの観察を行った。電子線の照射により、バブルの表面電荷を制御し、その反応活性を 制御することについて検討した。本研究の成果は、これまでは観察が困難であった液中のソフトマテリアルを高分解能で観察する手法として多くの分野への応用展開が期待できる。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (33 results)

All 2019 2018 2017 2016

All Journal Article (10 results) (of which Peer Reviewed: 10 results,  Open Access: 1 results) Presentation (23 results) (of which Int'l Joint Research: 10 results,  Invited: 20 results)

  • [Journal Article] Highly Luminescent YAIO3:Gd3+ Thin Films as a Nanoscale Optical Source for Super-Resolution Bioimating2019

    • Author(s)
      Mykyta Kolchiba, Wataru Inami, Yoshimasa Kawata
    • Journal Title

      Optical Material Express

      Volume: 9 Issue: 4 Pages: 1803-1814

    • DOI

      10.1364/ome.9.001803

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Time-Resolved Four-Tap Lock-In Pixel CMOS Image Sensor for Real-Time Fluorescence Lifetime Imaging Microscopy2018

    • Author(s)
      Seo Min-Woong、Shirakawa Yuya、Kawata Yoshimasa、Kagawa Keiichiro、Yasutomi Keita、Kawahito Shoji
    • Journal Title

      IEEE Journal of Solid-State Circuits

      Volume: 53 Issue: 8 Pages: 2319-2330

    • DOI

      10.1109/jssc.2018.2827918

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Photothermally Active Upconversion Core-Shell NaGdF4:Yb:Tm@Cu Nanostructures: Synthesis and Theranostic Properties2018

    • Author(s)
      Ibrahim Khaleelullah Mohamed Mathar Sahib、Tanaka Asahi、Dheivasigamani Thangaraju、Sugimoto Kyohei、Shimura Yosuke、Inami Wataru、Kawata Yoshimasa、Hayakawa Yasuhiro
    • Journal Title

      Particle & Particle Systems Characterization

      Volume: 35 Issue: 11 Pages: 1800227-1800227

    • DOI

      10.1002/ppsc.201800227

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescence Lifetime Measurement Excited with Ultraviolet Surface Plasmon Resonance2018

    • Author(s)
      Hanulia Taras、Inami Wataru、Ono Atsushi、Kawata Yoshimasa
    • Journal Title

      Optics Communications

      Volume: 427 Pages: 266-270

    • DOI

      10.1016/j.optcom.2018.06.069

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatial resolution and cathodoluminescence intensity dependence on acceleration voltage in electron beam excitation assisted optical microscopy using Y2O3:Eu3+ film2017

    • Author(s)
      Yoichiro Nakanishi, Hiroko Kominami,Yoshimasa Kawata,Wataru Inami,Atsushi Sugita,Masashi Kamiya
    • Journal Title

      Ultramicroscopy

      Volume: 182 Pages: 212-215

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative Phase Imaging by Optimized Asymmetric Illumination2017

    • Author(s)
      Yoshimasa Suzuki, Mayumi Odaira,Hisashi Ohde,Yoshimasa Kawata
    • Journal Title

      Applied Optics

      Volume: 56

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multi-modal imaging of HeLa cells using a luminescent ZnS:Mn/NaGdF4:Yb:Er nanocomposite with enhanced upconversion red2016

    • Author(s)
      Dheivasigamani Thangaraju, Yuriko Masuda, Ibrahim Khaleelullah Mohamed Mathar Sahib, Wataru Inami, Yoshimasa Kawata, Yasuhiro Hayakawa
    • Journal Title

      RSC Advances

      Volume: 6 Pages: 33569-33579

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cell structure imaging with bright and homogeneous nanometric light source2016

    • Author(s)
      Masahiro Fukuta, Atsushi Ono, Yasunori Nawa, Wataru Inami, Yoshimasa Kawata, Susumu Terekawa
    • Journal Title

      Biophotonics

      Volume: 9 Pages: 1-8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Label-free cellular structure imaging with 82 nm lateral resolution using an electron-beam excitation-assisted optical microscope2016

    • Author(s)
      Masahiro Fukuta, Yuriko Masuda, Wataru Inami, Yoshimasa Kawata
    • Journal Title

      Optics Express

      Volume: 24 Pages: 16487-16495

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct optical measurements of far- and deep- ultraviolet surface plasmon resonance with different refractive indices2016

    • Author(s)
      Koji Watari, Takeyoshi Goto, Masakazu Kikawada, Wataru Inami, Yoshimawa Kawata, Yukihiro Ozaki
    • Journal Title

      Optics Express

      Volume: 24 Pages: 21886-21896

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] High Resolution Bio-imaging of Non-Stained Cells with Electron Beam Excitation2019

    • Author(s)
      Yoshimasa Kawata
    • Organizer
      5th International Conference on Nanoscience and Nanotechnology (ICONN2019)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] High Resolution Bio-Imaging of Non-Stained Cells with Electron Beam Excitation2019

    • Author(s)
      Yoshimasa Kawata
    • Organizer
      Joint Student Scientific Seminar Between Faculty of Engineering & Physics of Amur State University, Russia and Faculty of Engieering of National University Corporation Shizuoka University, Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 電子線励起アシスト超解像顕微鏡2019

    • Author(s)
      川田善正
    • Organizer
      第45回冬期講習会「光と生命科学」
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 光を用いた超解像バイオイメージング2019

    • Author(s)
      川田善正
    • Organizer
      東三河・浜松地区高大連携協議会フォーラム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 電子線励起蛍光顕微鏡2019

    • Author(s)
      川田善正、居波 渉
    • Organizer
      マイクロビームアナリシス 第141委員会 第175回 研究会資料 日本学術振興会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 電子線励起による超解像光学顕微鏡2019

    • Author(s)
      川田善正
    • Organizer
      特定非営利活動法人 日本フォトニクス協議会, JPC アカデミック・パートナーシップ・ゼミナール (APS) 第5回 「静岡大学 -次世代イメージングを目指したひかり技術-」のご案内
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Electron Beam Addressable Potentiometric Sensor for Ion Distribution Imaging with High Resolution2018

    • Author(s)
      Wataru Inami, Kiyohisa Nii, Satoru Shibano, Yoshimasa Kawata
    • Organizer
      The 4th Biomedical Imaging and Sensing (Bisc2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] High Spatial Resolution Ion Imaging with Potentiometric Sensor Using an Electron Beam2018

    • Author(s)
      Wataru Inami, Kiyohisa Nii, Satoru Shibano, Hikaru Tomita, Yoshimasa Kawata, Yuji Miyahara
    • Organizer
      The 4th International Conference on Nano Electronics Research Education 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Optics and Photonics2018

    • Author(s)
      Yoshimasa Kawata
    • Organizer
      Intensive Course at National Taiwan University of Science and Technology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] バイオイメージングのための超解像顕微鏡の開発2018

    • Author(s)
      川田善正
    • Organizer
      浜松工業会 東京支部総会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 結像の評価と近接場光学2018

    • Author(s)
      川田善正
    • Organizer
      2018光応用技術研修会テキスト
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 電子線励起による超解像光学顕微鏡(EXA)の開発2018

    • Author(s)
      川田善正、居波 渉
    • Organizer
      第23回 福井セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 深紫外プラズモニクスと高感度バイオイメージング2018

    • Author(s)
      川田善正
    • Organizer
      光とレーザーの科学技術フェア2018」レーザーセミナー講演予稿集
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 紫外領域における表面プラズモン共鳴の現象研究とその応用2018

    • Author(s)
      川田善正
    • Organizer
      平成30年度多元技術融合光プロセス研究会第4回研究交流会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 電子線励起局在プラズモンを用いた蛍光の発光増強2018

    • Author(s)
      川田 善正,居波 渉,小野 篤史,山本 達也
    • Organizer
      情報フォトニクス研究会第12回関東学生研究論文講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 電子線産卵解析による3次元構造の測定2018

    • Author(s)
      川田 善正,居波 渉,山内 秀介
    • Organizer
      情報フォトニクス研究会第12回関東学生研究論文講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] High Resolution Imaging with Electron Beam Assisted (EXA) Micrscopy for Bio Technology2017

    • Author(s)
      Yoshimasa Kawata,Wataru Inami,Masahiro Fukuta
    • Organizer
      The 25th International Conference on Advanced Laser Technologies (ALT’17)
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Highly Luminescent YAP Thin Films as Nanoscale Optical Source for Ultra-High Resolution Microscopy2017

    • Author(s)
      Yoshimasa Kawata,Wataru Inami,Mykyta Kolchiba
    • Organizer
      The 78th JSAP Autumn Meeting
    • Related Report
      2017 Annual Research Report
  • [Presentation] High Resolution Optical Microscopy for Bio-Imaging with Electron Beam Excitation2016

    • Author(s)
      Yoshimasa Kawata, Masahiro Fukuta, Wataru Inami
    • Organizer
      Global Nanophotonics 2016
    • Place of Presentation
      大阪府立国際会議場(大阪府大阪市)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] High Resolution Imaging with Electron Beam Excitation2016

    • Author(s)
      Yoshimasa Kawata, Masahiro Fukuta, Wataru Inami
    • Organizer
      International Symposium on Optical Memory 2016
    • Place of Presentation
      京都リサーチパーク(京都府京都市)
    • Year and Date
      2016-10-16
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Deep-UV Plasmonics for High Senstive Bio-Imaging2016

    • Author(s)
      Yoshimasa Kawata, Mazakazu Kikawada, Atsushi Ono, Wataru Inami
    • Organizer
      15th Asia-Pacific Conference on Fundamental Problems of Opto- and Microelectronics
    • Place of Presentation
      Far Eastern State Transport University, Khavarovsk, Russia
    • Year and Date
      2016-10-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Deep-UV Surface Plasmon for Bio-Imaging2016

    • Author(s)
      Yoshimasa Kawata, Mazakazu Kikawada, Atsushi Ono, Wataru Inami
    • Organizer
      SCIX2016
    • Place of Presentation
      Hyatt Regency Hotel, Minneapolis, MN, USA
    • Year and Date
      2016-09-18
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Sensitive Imaging of Organellas in Label-Free Cells by Surface Plasmon Resonance in Deep-Ultraviolet Region2016

    • Author(s)
      Yoshimasa Kawata, Mazakazu Kikawada, Atsushi Ono, Wataru Inami
    • Organizer
      SPIE Optics + Photonics UV and Higher Energy Photonics
    • Place of Presentation
      San Diego Convention Center, San Diego, California, USA
    • Year and Date
      2016-08-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited

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Published: 2016-04-21   Modified: 2020-03-30  

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