Process development by using the optimization of inclusion and crystallization of fulleren

• Project/Area Number: 16H04561
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Reaction engineering/Process system
• Research Institution: Sojo University
• Principal Investigator: KUSAKABE Katsuki 崇城大学, 工学部, 教授 (30153274)
• Co-Investigator(Kenkyū-buntansha): 櫻木 美菜 (水谷美菜) 崇城大学, 工学部, 准教授 (90646829)
• Project Period (FY): 2016-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000); Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2017: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000); Fiscal Year 2016: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
• Keywords: 機能性材料 / 多孔質材料 / 結晶材料 / 両親媒性 / ナノ孔 / 固体蛍光物質 / ナノリアクター / オリゴマー / フラーレン / 両親媒性ナノ孔結晶 / 包接化合物 / 蛍光特性 / シクロデキストリン / 多孔質有機結晶 / 両親媒性ナノ孔 / 金属有機構造体 / 多孔質結晶 / 晶析 / ナノ粒子 / 蛍光 / ナノチューブ・フラーレン / 反応・分離工学 / 太陽電池 / 複合材料・物性 / 結晶成長

Outline of Final Research Achievements

Cyclodextrin-based metal organic framework (CD-MOF) is a porous nanoporous crystal. In CD-MOF, advanced encapsulation methods were established to introduce water-soluble porphyrins into hydrophilic nanopores and fullerene C60 into the hydrophobic nanopores. Finally, oxidative polymerization of the thiophene compound in CD-MOF was carried out. It was revealed that oligomers of 5 or less were formed without further progress of polymerization.

Academic Significance and Societal Importance of the Research Achievements

電子材料として注目されるC60の孤立、水溶化法としてCD-MOF内のナノ孔への導入法が確立され、今後C60の触媒分野や医薬分野への応用が期待できる。また、CD-MOFは欠陥がなく結晶性が高いので、物質合成のためのナノリアクターとして機能する。本研究では重合反応によりオリゴマーの合成を行ったが、サイズが2nm以下の貴金属ナノクラスターや非晶質金属酸化物ナノクラスターなどの超機能性材料の合成が可能である。

Research Products

• [Journal Article] Encapsulation of Isolated C60 Molecules in a Cyclodextrin-based Metal-Organic Framework (2018)
  • Author(s): A. Nagai, S. Tsutsumi, W. Michida, M. Sakuragi, K. Mizuki, K. Kusakabe
  • Journal Title: JOURNAL OF CHEMICAL ENGINEERING OF JAPAN Volume: 51 Issue: 7 Pages: 615-619
  • DOI: 10.1252/jcej.17we333
  • NAID: 130007401909
  • ISSN: 0021-9592, 1881-1299
  • Year and Date: 2018-07-20
  • Peer Reviewed
• [Journal Article] Fluorescent Properties of Fluorescein and Rhodamine B in Cyclodextrin-Based Metal-Organic Framework (2018)
  • Author(s): 道田 航, 永井杏奈, 酒村知至, 櫻木美菜, 水城圭司, 草壁克己
  • Journal Title: KAGAKU KOGAKU RONBUNSHU Volume: 44 Issue: 3 Pages: 161-165
  • DOI: 10.1252/kakoronbunshu.44.161
  • NAID: 130006742937
  • ISSN: 0386-216X, 1349-9203
  • Year and Date: 2018-05-20
  • Peer Reviewed
• [Journal Article] Adsorption behavior of aromatic carboxylic acids on a cyclodextrin-based metal-organic framework (2018)
  • Author(s): A. Nagai, W. Michida, M. Sakuragi, M. Nishida, G. Guan, K. Kusakabe
  • Journal Title: International Journal of Biomass & Renewables Volume: 1 Pages: 17-23
  • Peer Reviewed
• [Journal Article] Polymerization of 3,4-Ethylenedioxythiophene in Cyclodextrin-Based Metal-Organic Framework (2018)
  • Author(s): Wataru Michida, Anna Nagai, Mina Sakuragi, Katsuki Kusakabe
  • Journal Title: Crystal Research and Technology Volume: - Issue: 4
  • DOI: 10.1002/crat.201700142
  • Peer Reviewed
• [Journal Article] シクロデキストリン系金属有機構造体中のフルオレセインとローダミンBの蛍光特性 (2018)
  • Author(s): 道田 航、永井杏奈、酒村知至、櫻木美菜、水城圭司、草壁克己
  • Journal Title: 化学工学論文集 Volume: -
  • NAID: 130006742937
  • Peer Reviewed
• [Journal Article] Encapsulation of Isolated C60 Molecules in Cyclodextrin-based Metal-Organic Framework (2018)
  • Author(s): Anna Nagai, Shinsuke Tsutsumi, Wataru Michida, Mina Sakuragi, Keiji Mizuki, Katsuki Kusakabe
  • Journal Title: Journal of Chemical Engineering Japan Volume: -
  • NAID: 130007401909
  • Peer Reviewed
• [Journal Article] Preparation of Mesoporous Titania by a Sol-gel Method in a Deep Eutectic Solvents (2018)
  • Author(s): Katsuki Kusakabe, Yuki Mitsutake, Wataru Michida, Mina Sakuragi
  • Journal Title: Journal of Chemical Engineering Japan Volume: -
  • Peer Reviewed
• [Journal Article] Adsorption behavior of aromatic carboxylic acids on a cyclodextrin-based metal-organic framework (2018)
  • Author(s): Anna Nagai, Wataru Michida, Mina Sakuragi, Masashi Nishida, Guoqing Guan, Abuliti Abudula, Katsuki Kusakabe
  • Journal Title: International Journal of Biomass & Renewals Volume: -
  • Peer Reviewed
• [Journal Article] Crystal Growth of Cyclodextrin-based Metal-organic Framework for Carbon Dioxide Capture and Separation (2016)
  • Author(s): Ton Kar Yan, Anna Nagai, Wataru Michida, Katsuki Kusakabe, Suzana binti Yusup
  • Journal Title: Procedia Engineering Volume: 148 Pages: 30-34
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] 多孔質結晶のナノ孔内でのパラジウムの合成とその複合触媒を用いたスズキカップリング反応 (2018)
  • Author(s): 千本皓祐,永井杏奈,道田航,櫻木美菜,草壁克己
  • Organizer: 第55回化学関連支部合同九州大会
• [Presentation] 共役電子系分子で合成したナノ孔結晶 (2018)
  • Author(s): 永井杏奈, 道田 航, 櫻木美菜, 草壁克己
  • Organizer: 第29回化学工学会九州支部若手エンジニアリング討論会
• [Presentation] CD-MOF内での導電性ポリマーの合成 (2018)
  • Author(s): 長尾啓史, 道田 航, 櫻木美菜, 草壁克己
  • Organizer: 第29回化学工学会九州支部若手エンジニアリング討論会
• [Presentation] Pdナノクラスター/CD-MOFによるスズキカップリング反応 (2018)
  • Author(s): 千本皓祐, 道田 航, 櫻木美菜, 草壁克己
  • Organizer: 第29回化学工学会九州支部若手エンジニアリング討論会
• [Presentation] New Porous Materials for Nano-chemical Engineering (2018)
  • Author(s): K. Kusakabe
  • Organizer: 8th SOJO-UTP Joint Seminar on Nano and Bio Research
  • Int'l Joint Research
• [Presentation] ナノリアクターとしての有機ナノ孔結晶 (2018)
  • Author(s): 草壁克己、道田 航、永井杏奈、櫻木美菜
  • Organizer: 化学工学会第50回 秋季大会
• [Presentation] 金システィン錯体を導入したCD-MOFの蛍光特性 (2018)
  • Author(s): 道田 航、永井杏奈、櫻木美菜、草壁克己
  • Organizer: 化学工学会第50回 秋季大会
• [Presentation] 機能性分子を導入したCD-MOFを用いた有機反応の特性 (2018)
  • Author(s): 永井杏奈、道田 航、櫻木美菜、草壁克己
  • Organizer: 化学工学会第50回 秋季大会
• [Presentation] CD-MOF内での導電性ポリマーの合成 (2018)
  • Author(s): 長尾啓史、道田 航、櫻木美菜、草壁克己
  • Organizer: 化学工学会第50回 秋季大会
• [Presentation] Pdナノクラスター/CD-MOFによるスズキカップリング反応 (2018)
  • Author(s): 千本皓祐、道田 航、櫻木美菜、草壁克己
  • Organizer: 化学工学会第50回 秋季大会
• [Presentation] The flow reactor finally stopped flowing (2018)
  • Author(s): K. Kusakabe
  • Organizer: KIChE 2018 Autumn Meeting
  • Int'l Joint Research / Invited
• [Presentation] Polymerization of thiophene compounds in nanochannel of CD-MOF (2018)
  • Author(s): K. Nagao, W. Michida, M. Sakuragi, K. Kusakabe
  • Organizer: 31st International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Reduction of nitrobenzene over Ni/C60@CD-MOF composite catalyst (2018)
  • Author(s): A. Nagai, W. Michida, M. Sakuragi, K. Kusakabe
  • Organizer: 31st International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Synthesis of Au nanocluster in CD-MOF for detecting aromatic nitro compounds (2018)
  • Author(s): W. Michida, A. Nagai, M. Sakuragi, K. Kusakabe
  • Organizer: 31st International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Recrystallization behavior of CD-MOF in methanol (2017)
  • Author(s): Anna Nagai, Keishi Nagao, Wataru Michida, Mina Sakuragi, Katsuki Kusakabe
  • Organizer: 30th International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Encapsulation of large molecules in cyclodextrin-based metal-organic framework (2017)
  • Author(s): Katsuki Kusakabe, Wataru Michida, Anna Nagai, Mina Sakuragi
  • Organizer: 2017Korea/Japan/Taiwan Chemical Engineering Conference
  • Int'l Joint Research
• [Presentation] シクロデキストリン系金属有機構造体中での3,4-エチレンジオキシチオフェンの重合 (2017)
  • Author(s): 道田 航、永井杏奈、櫻木美菜、草壁克己
  • Organizer: 化学工学会第47回 秋季大会
• [Presentation] Polymerization of 3,4-Ethylenedioxythiophene in Cyclodextrin-based Metal-Organic Framework (2017)
  • Author(s): Wataru Michida, Anna Nagai, Mina Sakuragi, Katsuki Kusakabe
  • Organizer: Asian Pacific Conference on Chemical Engineering 2017
  • Int'l Joint Research
• [Presentation] Crystallization of α-CD/KOH/H3BO3 solution by vapor diffusion method (2017)
  • Author(s): Keishi Nagao, Anna Nagai, Wataru Michida, Mina Sakuragi, Katsuki Kusakabe
  • Organizer: 7th SOJO-UTP Joint Seminar on Nano and Bio Research
  • Int'l Joint Research
• [Presentation] 蒸気拡散法によるα-CD/KOH/H3BO3水溶液からの結晶析出 (2017)
  • Author(s): 長尾啓史、永井杏奈、道田 航、櫻木美菜、草壁克己
  • Organizer: 第52回化学関連支部合同九州大会
• [Presentation] フラーレン/シクロデキストリン包接錯体からのCD-MOFの結晶成長 (2017)
  • Author(s): 堤 信介、永井杏奈、道田 航、櫻木美菜、草壁克己
  • Organizer: 第52回化学関連支部合同九州大会
• [Presentation] Polymerization of 3,4-ethylenedioxythiophene in CD-MOF (2017)
  • Author(s): Wataru Michid, Anna Nagai, Mina Sakuragi, Katsuki Kusakabe
  • Organizer: 253rd ACS National Meeting & Exposition
  • Int'l Joint Research
• [Presentation] Fluorescent emission from dye-doped CD-MOF at solid state (2016)
  • Author(s): K. Nagao, T. Sakemura, A. Nagai, W. Michida, M. Sakuragi, K. Kusakabe
  • Organizer: 29th International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Crystallization of fullerene-doped CD-MOF (2016)
  • Author(s): S. Tsutsumi, A. Nagai, W. Michida, M. Sakuragi, K. Kusakabe
  • Organizer: 29th International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Synthesis and Characterization of double-doped CD-MOF (2016)
  • Author(s): A. Nagai, W. Michida, M.Sakuragi, K. Kusakabe
  • Organizer: 29th International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] Polymerization of 3,4-ethylenedioxythiophene in CD-MOF (2016)
  • Author(s): W. Michida, A. Nagai, M. Sakuragi, K. Kusakabe
  • Organizer: 29th International Symposium on Chemical Engineering
  • Int'l Joint Research
• [Presentation] 蛍光分子を包接したシクロデキストリン系MOFの合成 (2016)
  • Author(s): 道田 航、酒村知至、永井杏奈、櫻木美菜、草壁克己
  • Organizer: 化学工学会第46回 秋季大会
• [Presentation] シクロデキストリン系MOFへのフラーレンとポルフィリンの固定化 (2016)
  • Author(s): 永井杏奈、道田 航、櫻木美菜、草壁克己
  • Organizer: 化学工学会第46回 秋季大会
• [Presentation] Inclusion of conjugated molecules in cyclodextrin-based nanoporous crystal (2016)
  • Author(s): A. Nagai, W. Michida, M. Sakuragi, K. Kusakabe
  • Organizer: 6th SOJO-UTP Joint Seminar on Nano and Bio Research
  • Int'l Joint Research
• [Presentation] Fluorescence characteristics of fluorescein and rhopdamine B in cyclodextrin-based metal-organic framework (2016)
  • Author(s): K. Kusakabe, T. Sakemura, W. Michida, M. Sakuragi
  • Organizer: 6th SOJO-UTP Joint Seminar on Nano and Bio Research
  • Int'l Joint Research
• [Presentation] Crystal growth of cyclodextrin-based metal-organic framework for carbon dioxide capture and separation (2016)
  • Author(s): T. K. Yan, A. Nagai, W. Michida, K. Kusakabe, S. Yusup
  • Organizer: International Conderence of Process Engineering & Applied Materials 2016
  • Int'l Joint Research
• [Presentation] γ-シクロデキストリンと共役電子系分子で合成したナノ孔結晶 (2016)
  • Author(s): 永井杏奈、道田 航、櫻木美菜、草壁克己
  • Organizer: 第51回化学関連支部合同九州大会