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Elucidation of pathophysiology of auditory processing disorders and establishment of objective diagnostic tool

Research Project

Project/Area Number 16H05478
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionTohoku University

Principal Investigator

Kawase Tetsuaki  東北大学, 医工学研究科, 教授 (50169728)

Co-Investigator(Kenkyū-buntansha) 菅野 彰剛  東北大学, 医学系研究科, 講師 (20578968)
小渕 千絵  国際医療福祉大学, 保健医療学部, 准教授 (30348099)
坂本 修一  東北大学, 電気通信研究所, 教授 (60332524)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2019: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Keywords聴覚情報処理障害 / 注意障害 / 聴覚情景分析 / 脳磁図 / MRI / 脳波 / 構造解析
Outline of Final Research Achievements

Auditory processing disorder (APD) is a pathological condition that presents listening difficulties especially under background noise, despite displaying normal or near-normal hearing acuity. In this study, we investigated to elucidate the pathophysiology of APD by neurophysiological and psychoacoustic approaches, and tried to establish objective diagnostic methods based on the pathological condition. The following findings were obtained; i.e., 1)usefulness of spatial listening tests such as word intelligibility evaluation using a three-dimensional speaker array, 2) effectiveness of spatial and temporal cue presentation in improving listening of this patient, 3) limitation of hearing assessment using headphone system, and 4) the usefulness of the attention / ignorance function evaluation method using magnetoencephalography.

Academic Significance and Societal Importance of the Research Achievements

本研究では、聴覚情報処理障害を聴覚情景分析能の不全という立場から研究を進め、ヘッドフォン下の聞き取り検査では大きな異常を示さない場合においても、スピーカーアレイを用いた空間的聴覚機能検査のでは高率に異常を呈することを初めて明らかにするとともに、聴覚的注意に関連した空間的、時間的手がかりが、本症患者の聞き取り改善に有用であることも併せて示し、聴覚情報処理障害の診断、患者の取り扱いへのあらたな指針を提言することができた。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (15 results)

All 2019 2018 2017 2016

All Journal Article (5 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (10 results) (of which Int'l Joint Research: 1 results,  Invited: 7 results)

  • [Journal Article] 診療に役立つ聴覚メカニズム2019

    • Author(s)
      川瀬 哲明
    • Journal Title

      日本耳鼻咽喉科学会会報

      Volume: 122 Pages: 1461-1463

    • Related Report
      2019 Annual Research Report
  • [Journal Article] 聴覚障害の診断と治療 最近の話題から2019

    • Author(s)
      川瀬 哲明
    • Journal Title

      宮城県医師会報

      Volume: 886 Pages: 836-840

    • Related Report
      2019 Annual Research Report
  • [Journal Article] 聴覚臨床に役立つ聴覚メカニズムの知識 音受容から聴覚情景分析まで2018

    • Author(s)
      川瀬哲明
    • Journal Title

      Audiology Japan

      Volume: 61 Pages: 177-186

    • NAID

      130007432834

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Visual Speech on Early Auditory Evoked Fields - From the Viewpoint of Individual Variance.2017

    • Author(s)
      Yahata I, Kawase T, Kanno A, Hidaka H, Sakamoto S, Nakasato N, Kawashima R, Katori Y.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 1 Pages: 170166-170166

    • DOI

      10.1371/journal.pone.0170166

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impact of audio-visual asynchrony on lip-reading effects -neuromagnetic and psychophysical study.2016

    • Author(s)
      Kawase T, Yahata I, Kanno A, Sakamoto S, Takanashi Y, Takata S, Nakasato N, Kawashima R, Katori Y
    • Journal Title

      PLoS One

      Volume: 28 Issue: 12 Pages: e0168740-e0168740

    • DOI

      10.1371/journal.pone.0168740

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 難聴病態とマスキング特性2019

    • Author(s)
      川瀬哲明
    • Organizer
      内耳ひずみ研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 聴覚情報処理障害を疑った患者に対するスピーカアレイを用いた競合音声下単語了解度検査2019

    • Author(s)
      川瀬 哲明, 寺岡 諒, 佐々木 志保, 小渕 千絵, 坂本 修一
    • Organizer
      日本聴覚医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 聴性誘発脳磁界N100mに対する対側耳音刺激の影響2019

    • Author(s)
      白倉真之、菅野彰剛、中里信和、川島隆太、香取幸夫、川瀬哲明
    • Organizer
      MICONS2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 聴覚情報処理障害2019

    • Author(s)
      川瀬哲明
    • Organizer
      日本耳鼻咽喉科学会宮城県地方部会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 聴覚障害の診断と治療-最近の話題から-2019

    • Author(s)
      川瀬哲明
    • Organizer
      宮城県医師会冬季医学講座
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 感音難聴の診断2018

    • Author(s)
      川瀬哲明
    • Organizer
      日本耳鼻咽喉科学会総会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 診療に役立つ聴覚メカニズム2018

    • Author(s)
      川瀬哲明
    • Organizer
      日本耳鼻咽喉科学会専門医講習会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Impact of audio-visual asynchrony on lip-reading effects2017

    • Author(s)
      Tetsuaki Kawase, Izumi Yahata, Akitake Kanno, Nobukazu Nakasato, Ryuta Kawashima and Yukio Katori
    • Organizer
      Bimagnetic Sendai 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 聴性誘発脳磁界に観察されるlip-reading効果2017

    • Author(s)
      川瀬哲明
    • Organizer
      第56回日本生体医工学会大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 聴覚臨床に役立つ聴覚メカニズムの知識‐音受容から聴覚情景分析まで‐2017

    • Author(s)
      川瀬哲明
    • Organizer
      日本聴覚医学会
    • Related Report
      2017 Annual Research Report
    • Invited

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Published: 2016-04-21   Modified: 2021-02-19  

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