| Budget Amount *help |
¥23,790,000 (Direct Cost: ¥18,300,000、Indirect Cost: ¥5,490,000)
Fiscal Year 2019: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2018: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
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| Outline of Final Research Achievements |
The follicular cyst, one of the most important reproductive disorders in cattle, is suggested to be partly caused by the defect of gonadotropin-releasing hormone (GnRH) surge generator that induces ovulation in the brain. However, the mechanism regulating the GnRH surge generator has not been elucidated especially in domestic animals. This study aimed to clarify the mechanism regulating the GnRH surge generator in domestic ruminants. I succeeded to establish cell lines (kisspeptin neuron cell lines and GnRH neuron cell lines) that can be used to analyze the regulation mechanism of reproductive center in domestic ruminants at a cellular level.
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