| Budget Amount *help |
¥180,960,000 (Direct Cost: ¥139,200,000、Indirect Cost: ¥41,760,000)
Fiscal Year 2020: ¥28,860,000 (Direct Cost: ¥22,200,000、Indirect Cost: ¥6,660,000)
Fiscal Year 2019: ¥38,480,000 (Direct Cost: ¥29,600,000、Indirect Cost: ¥8,880,000)
Fiscal Year 2018: ¥38,220,000 (Direct Cost: ¥29,400,000、Indirect Cost: ¥8,820,000)
Fiscal Year 2017: ¥37,050,000 (Direct Cost: ¥28,500,000、Indirect Cost: ¥8,550,000)
Fiscal Year 2016: ¥38,350,000 (Direct Cost: ¥29,500,000、Indirect Cost: ¥8,850,000)
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| Outline of Final Research Achievements |
Autism is a developmental disorder with impaired social skills. It is a multifactorial complex disorder with a high genetic contribution, but the involvement of environmental factors cannot be denied, and the elucidation of its pathophysiology is still incomplete. In this study, we clarified one aspect of autism pathology by conducting multidisciplinary analysis at the cellular/synaptic (development of autistic cell models), circuit/behavioral (clarification of neural circuits for abnormal social behavior), and environmental factors (disorders of brain development due to brain-gut interactions) levels, incorporating methodologies that employ the most advanced technologies for each.
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