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Prostate stereotactic body radiotherapy with a hydrogel spacer

Research Project

Project/Area Number 16H06756
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionThe University of Tokyo

Principal Investigator

Ogita Mami  東京大学, 医学部附属病院, 助教 (60779784)

Project Period (FY) 2016-08-26 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords前立腺癌 / 定位放射線治療 / ハイドロゲルスペーサー / 放射線
Outline of Final Research Achievements

Rectal toxicities are major concerns in radiotherapy for prostate cancer. We conducted this phase II clinical trial to evaluate the safety and the efficacy of stereotactic body radiotherapy (SBRT) for prostate cancer with the use of hydrogel spacers, which may reduce rectal toxicities by pushing the rectum away from the prostate. This is the first study using the hydrogel spacers in Japanese population, and we found the hydrogel spacers can be safely applied to Japanese prostate cancer patients. As there have been few reports of the hydrogel spacers in SBRT, our study provided important data. We will continue to follow up the study participants, and evaluate the safety and the efficacy of the hydrogel spacers in SBRT in prostate cancer patients.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • Research Products

    (5 results)

All 2018 2017 Other

All Journal Article (1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results) Remarks (1 results)

  • [Journal Article] 前立腺癌放射線治療の直腸障害低減を可能にした 特定保健医療材料「SpaceOAR ハイドロゲル」2017

    • Author(s)
      扇田真美、山下英臣、中川恵一
    • Journal Title

      新医療

      Volume: 512 Pages: 124-127

    • Related Report
      2017 Annual Research Report
  • [Presentation] Five year follow-up of prostate cancer patients treated with volumetric modulated arc therapy (VMAT)2018

    • Author(s)
      M. Ogita, K. Yamamoto, K. Shiraishi, S. Sawayanagi, H. Yamashita, K. Nakagawa
    • Organizer
      ESTRO 37
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preliminary Results of VMAT Stereotactic Body Radiotherapy with Flattening F ilter-free Beam for Prostate Cancer2017

    • Author(s)
      Mami Ogita, Hideomi Yamashita, Keiichi Nakagawa
    • Organizer
      日本放射線学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 前立腺癌に対するFFF-VMAT定位放射線治療の有害事象2017

    • Author(s)
      扇田真美、山下英臣、中川恵一
    • Organizer
      日本放射線腫瘍学会
    • Related Report
      2017 Annual Research Report
  • [Remarks] 前立腺癌に対する特定臨床研究のお知らせ

    • URL

      http://www.u-tokyo-rad.jp/2017/02/17180446.html

    • Related Report
      2016 Annual Research Report

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Published: 2016-09-02   Modified: 2019-03-29  

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