| Project/Area Number |
16H06961
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Prosthodontics/ Dental materials science and
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2016-08-26 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | ブラキシズム / ストレス / 睡眠 / リズム性咀嚼筋活動 / 歯学 / 歯科 / 睡眠時ブラキシズム |
|---|
| Outline of Final Research Achievements |
Rhythmic masticatory muscle activity (RMMA) was found to occur during NREM sleep in guinea pigs.Physiological characteristics were similar to RMMA in humans, as the occurrence of RMMA was associated with arousal processes. Electromyographic characteristics of RMMA in guinea pigs were also similar to those in humans. Using this animal model, experimental stress was given to the freely moving guinea pigs. During two hours after experimental stress, animals had less sleep but more RMMA. After then, these variables returned to the baseline level (i.e., without stress). Rhythmic masseter activity was found to be triggered when micro-electrical stimulations were given to the ventral areas of amygdala in anesthetized guinea pigs. These suggest that experimental stress can increase the generation of RMMA and the roles of amygdala need to be investigated in the future study.
|
