| Project/Area Number |
16H07196
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Prosthodontics/ Dental materials science and
|
|---|
| Research Institution | Showa University |
|---|
Principal Investigator |
Ikeya Kenji 昭和大学, 歯学部, 助教 (30783344)
|
|---|
| Research Collaborator |
石原 一彦 東京大学, 大学院工学系研究科マテリアル工学専攻, 教授
井上 祐貴 東京大学, 大学院工学系研究科マテリアル工学専攻, 助教
桑田 啓貴 昭和大学, 口腔微生物学教室, 教授
森崎 弘史 昭和大学, 口腔微生物学教室, 講師
山本 隆司 サンメディカル株式会社
|
|---|
| Project Period (FY) |
2016-08-26 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | PMBPAz / MPCポリマー / デンチャープラーク / PMBPAzポリマー / 超親水性ポリマー / バイオマテリアル / denture plaque / biomaterial / 歯学 / バイオ関連機器 |
|---|
| Outline of Final Research Achievements |
The mean ±SD percentage of plaque index was 40.7% ±19.9% on the mucosal surfaces and 28.0% ±16.8% on the polished surfaces of the control denture. The mean percentage of plaque index of PMBPAz-treated dentures significantly decreased to 17.4%% ±12.0% on the mucosal surfaces (P<.001) and 15.0% ±9.9% on the polished surfaces (P<.05). These results demonstrated the effectiveness of the treatment with the PMBPAz to inhibit the bacterial plaque deposition on complete dentures.
Denture plaque-associated infection is an issue of considerable importance for denture wearers. Treatment with PMBPAz on denture surfaces is a promising, straightforward, and safe method of preventing microbial contamination on removable dentures.
|
