• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Study of repair and regeneration of tooth, alveolar bone and bone by CO2 laser with controlled laser pulse waveform

Research Project

Project/Area Number 16K01352
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionUniversity of Yamanashi

Principal Investigator

UNO Kazuyuki  山梨大学, 大学院総合研究部, 准教授 (20550768)

Co-Investigator(Kenkyū-buntansha) 河阪 明彦  山梨大学, 大学院総合研究部, 助教 (30710313)
諸井 明徳  山梨大学, 大学院総合研究部, 講師 (60645141)
Research Collaborator AKITSU Tetsuya  
KOUSAKA Akihiko  
TAKAYAMA Akihiro  
JITSUNO Takahisa  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
KeywordsCO2レーザー / レーザー医療 / 歯科口腔外科学 / 歯科 / 新生骨 / 歯学 / 再生医学 / 高性能レーザー / 光源技術
Outline of Final Research Achievements

We researched bone repair and tooth drilling by a CO2 laser with controlled laser pulse waveform. In bone repair, when the CO2 laser pulse with the spike pulse width of 360 ns, the pulse tail length of 92.6 μs and the energy ratio of the spike pulse to the pulse tail of 1:80 irradiated the surface of a rabbit nose bone, osteoblasts were formed near the maxillary sinus but not on the surface of the nasal bone. In tooth drilling, when the CO2 laser pulse with the spike pulse width of 337 ns, the pulse tail length of 180 μs and the energy ratio of the spike pulse to the pulse tail of 1:20 irradiated the surface of an extraction tooth of human, high efficient drilling without carbonization was realized.

Academic Significance and Societal Importance of the Research Achievements

本研究成果は,CO2レーザーの制御技術を用いた歯科口腔外科学における非侵襲・低侵襲な治療が可能なことを示すものである.インプラント治療において歯を支える歯槽骨の修復・再生は重要な課題である.本研究では,従来よりも熱影響の低い短パルスCO2レーザーでも,骨芽細胞が形成されることが明らかとなった.また,本研究では,従来の技術では歯牙に炭化を与えるために歯牙への治療には使用されていないCO2レーザーにおいて,従来よりも熱影響の低い短パルスCO2レーザーを使用し,炭化のない切削を実現した.CO2レーザーの制御により,国内外の研究者と比べて,エナメル質と象牙質ともに数倍から数十倍の高効率切削を実現した.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (10 results)

All 2018 2017 Other

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (3 results) (of which Invited: 1 results) Remarks (3 results)

  • [Journal Article] Longitudinally excited CO2 laser with short laser pulse and high quality beam2018

    • Author(s)
      Kazuyuki Uno, Jianhui Li, Hayato Goto, Takahisa Jitsuno
    • Journal Title

      Proceedings of SPIE

      Volume: 10518 Pages: 73-73

    • DOI

      10.1117/12.2288071

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 軸方向放電励起CO2レーザーの開発と人の歯の高効率切削2018

    • Author(s)
      宇野和行
    • Journal Title

      レーザー学会第517回研究会報告

      Volume: RTM-18

    • Related Report
      2017 Research-status Report
  • [Journal Article] Control of laser pulse waveform in longitudinally excited CO2 laser by adjustment of excitation circuit2018

    • Author(s)
      Uno Kazuyuki、Jitsuno Takahisa
    • Journal Title

      Optics & Laser Technology

      Volume: 101 Pages: 195-201

    • DOI

      10.1016/j.optlastec.2017.11.020

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dental hard tissue drilling by longitudinally excited CO2 laser2017

    • Author(s)
      Uno Kazuyuki、Yamamoto Takuya、Akitsu Tetsuya、Jitsuno Takahisa
    • Journal Title

      Proceedings of SPIE

      Volume: 10417 Pages: 104170U-104170U

    • DOI

      10.1117/12.2284944

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] 軸方向放電励起CO2レーザーの開発と応用2018

    • Author(s)
      宇野和行,實野孝久
    • Organizer
      レーザー学会第38回年次大会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 軸方向放電励起CO2レーザーの開発と人の歯の高効率切削2018

    • Author(s)
      宇野和行,實野孝久
    • Organizer
      レーザー学会第517回研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] 高ビーム品質・短パルスCO2レーザーによる人の歯の切削2017

    • Author(s)
      宇野和行
    • Organizer
      第64回応用物理学会春季学術講演会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Research-status Report
  • [Remarks] 宇野研究室のホームページ

    • URL

      http://www.ccn.yamanashi.ac.jp/~kuno/index.html

    • Related Report
      2018 Annual Research Report
  • [Remarks] 宇野研究室

    • URL

      http://www.ccn.yamanashi.ac.jp/~kuno/index.html

    • Related Report
      2017 Research-status Report
  • [Remarks] 山梨大学工学部電気電子工学科宇野研究室

    • URL

      http://www.ccn.yamanashi.ac.jp/~kuno/index.html

    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi