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Elucidation of the influence of nutritional status on sarcopenic dysphagia

Research Project

Project/Area Number 16K01460
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionYokohama City University

Principal Investigator

Wakabayashi Hidetaka  横浜市立大学, 附属市民総合医療センター, 講師 (80508797)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsサルコペニア / 摂食嚥下障害 / リハビリテーション栄養 / 嚥下障害 / リハビリテーション / 老化
Outline of Final Research Achievements

The purpose of the prospective cohort study was to assess the prevalence and prognosis of sarcopenic dysphagia in patients who require dysphagia rehabilitation. Participants were 108 patients referred to the Department of Rehabilitation Medicine for dysphagia rehabilitation. The Food Intake Level Scale (FILS) and a 5-step diagnostic algorithm for sarcopenic dysphagia was measured. The study included 72 males and 36 females (mean age 76). Comorbid diseases included brain and nervous system disease (36%), cardiovascular disease (25%), respiratory disease (14%), and cancer (11%). Median energy intake was 1159 kcal. Median FILS at admission and discharge was 4 and 8, respectively. Sarcopenic dysphagia was observed in 35 patients (32%). Ordered logistic regression analysis of the FILS at discharge adjusted for presence of sarcopenic dysphagia, age, gender, and the FILS at admission revealed that presence of sarcopenic dysphagia was independently associated with the FILS at discharge.

Academic Significance and Societal Importance of the Research Achievements

摂食嚥下リハの臨床現場では、サルコペニアの摂食嚥下障害の割合が高く、他の摂食嚥下障害と比較して機能予後が悪かった。そのため、超高齢社会の日本では摂食嚥下障害患者をみた場合、サルコペニアの摂食嚥下障害の可能性を必ず考慮して、リハ栄養の考え方で栄養改善しながら摂食嚥下リハを行うべきである。
2019年に日本サルコペニア・フレイル学会、日本摂食嚥下リハ学会、日本リハ栄養学会、日本嚥下医学会の4学会によって、「サルコペニアと摂食嚥下障害」のポジションペーパーが発表され、本研究領域に一定の発展を認めた(Fujishima I, et al. Geriatr Gerontol Int. 2019)。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (15 results)

All 2019 2018 2017

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (9 results) (of which Int'l Joint Research: 7 results,  Invited: 5 results)

  • [Journal Article] The prevalence and prognosis of sarcopenic dysphagia in patients who require dysphagia rehabilitation2019

    • Author(s)
      Wakabayashi H, Takahashi R, Murakami T.
    • Journal Title

      J Nutr Health Aging

      Volume: 23(1) Issue: 1 Pages: 84-88

    • DOI

      10.1007/s12603-018-1117-2

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rehabilitation nutrition for iatrogenic sarcopenia and sarcopenic dysphagia2019

    • Author(s)
      Nagano A, Nishioka S, Wakabayashi H.
    • Journal Title

      J Nutr Health Aging

      Volume: 23(3) Issue: 3 Pages: 256-265

    • DOI

      10.1007/s12603-018-1150-1

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence of sarcopenia and its association with dysphagia in cancer patients who require rehabilitation2017

    • Author(s)
      Wakabayashi H, Takahashi R, Watanabe N, Oritsu H, Shimizu Y.
    • Journal Title

      J Rehabil Med

      Volume: 49 Issue: 8 Pages: 682-685

    • DOI

      10.2340/16501977-2253

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development, reliability, and validity of a diagnostic algorithm for sarcopenic dysphagia2017

    • Author(s)
      Takashi Mori, Ichiro Fujishima, Hidetaka Wakabayashi, Masataka Itoda, Kenjiro Kunieda, Jun Kayashita, Shinta Nishioka, Akiko Sonoda, Yoshitoshi Kuroda, Minoru Yamada, Sumito Ogawa
    • Journal Title

      JCSM Clinical Reports

      Volume: 2

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prevalence of skeletal muscle mass loss and its association with swallowing function after cardiovascular surgery2017

    • Author(s)
      Wakabayashi H, Takahashi R, Watanabe N, Oritsu H, Shimizu Y.
    • Journal Title

      Nutrition

      Volume: 38 Pages: 70-73

    • DOI

      10.1016/j.nut.2017.01.010

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Occlusal support, dysphagia, malnutrition, and activities of daily living in aged individuals needing long-term care: a path analysis.2017

    • Author(s)
      Wakabayashi H, Matsushima M, Ichikawa H, Murayama S, Yoshida S, Kaneko M, Mutai R.
    • Journal Title

      The Journal of Nutrition Health and Aging

      Volume: 21 Issue: 1 Pages: 1-6

    • DOI

      10.1007/s12603-017-0897-0

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] The prevalence of nutritional risk and its association with rehabilitation outcome in older maintenance hemodialysis inpatients who require rehabilitation2018

    • Author(s)
      Wakabayashi H. Shimizu T.
    • Organizer
      19th Congress of the International Society of Renal Nutrition and Metabolism
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The prevalence and prognosis of sarcopenic dysphagia in patients who require dysphagia rehabilitation2018

    • Author(s)
      Wakabayashi H.
    • Organizer
      4th Asian Conference on Frailty and Sarcopenia
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rehabilitation nutrition for frailty and sarcopenia2018

    • Author(s)
      Wakabayashi H.
    • Organizer
      4th Asian Conference on Frailty and Sarcopenia
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Dysphagia in sarcopenia and head and neck cancer2018

    • Author(s)
      Wakabayashi H.
    • Organizer
      11th International Conference on Cachexia, Sarcopenia & Muscle Wasting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] サルコペニアの摂食嚥下障害の有病割合および栄養指標、ADLとの関連2018

    • Author(s)
      若林秀隆、髙橋理美子
    • Organizer
      第33回日本静脈経腸栄養学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Sarcopenic dysphagia2018

    • Author(s)
      Hidetaka Wakabayashi
    • Organizer
      7th European Society for Swallowing Disorders Congress
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Comprehensive management of OD in older people in acute care hospitals2018

    • Author(s)
      Hidetaka Wakabayashi
    • Organizer
      7th European Society for Swallowing Disorders Congress
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Rehabilitation Nutrition for Sarcopenia and Sarcopenic Dysphagia2018

    • Author(s)
      Hidetaka Wakabayashi
    • Organizer
      3rd Asian Conference for Frailty and Sarcopenia
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 心臓血管術後に嚥下障害を認めた患者の前サルコペニアと嚥下障害の関連2017

    • Author(s)
      若林秀隆、上野理美子、渡邉直子、折津英幸
    • Organizer
      第32回日本静脈経腸栄養学会学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2017-02-23
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2020-03-30  

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