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Development of an innovative SPECT system without the rotational data acquisition

Research Project

Project/Area Number 16K09025
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionHosei University

Principal Investigator

OGAWA Koichi  法政大学, 理工学部, 教授 (00158817)

Research Collaborator MOTOMURA nobutoku  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
KeywordsSPECT / 核医学 / ガンマカメラ / ピンホールコリメータ / データ収集 / モンテカルロ法 / 画像処理 / 画像再構成 / 時間放射能曲線 / リストモードデータ収集 / 放射性医薬品 / 静止型データ収集 / 動態イメージング / コリメータ / ピンホール
Outline of Final Research Achievements

A new single photons emission computed tomography(SPECT) apparatus was proposed in this study. This apparatus acquires gamma-ray data with three multi-pinhole collimators attached to a triple head gamma camera system without any rotational movement of gamma cameras around a patient. In this study, the performance of the proposed system was evaluated with simulations and experiments, and the relationship between the quality of reconstructed images and the parameters in the multi-pinhole collimator including the number of holes and the diameter of holes were clarified. In addition, brain and myocardial images reconstructed with this system were evaluated with numerical phantoms and experimental phantoms. And the availability of kinetic function analysis of an organ was also evaluated in this study.

Academic Significance and Societal Importance of the Research Achievements

本研究で提案するSPECT装置は3台のガンマ線検出器を患者の周囲に3角形状に配して全方向からのデータをマルチピンホールコリメータで収集する点に特徴があるが、これにより一度に患者の周りの全方向からのデータ収集が可能となる。これはSPECTでは不可能であった、放射性医薬品の動態情報を3次元画像として映像化することができることを意味し、従来、ポジトロンCT(PET)でしかできなかった動態解析がSPECTでもできるようになれば、検査のコストを下げ、SPECT検査の臨床適用が拡大すると考えられる。同時に患者の被ばく低減など核医学診断の質と有用性を大きく革新する可能性があるといえ、本研究の成果は大きい。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (15 results)

All 2018 2017 2016 Other

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (9 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results) Book (1 results) Remarks (2 results)

  • [Journal Article] List Mode Image Reconstruction With a Multi-pinhole Triple Head SPECT System2018

    • Author(s)
      Yohei Fujishiro, Kazumi Murata, Nobutoku Motomura, Koichi Ogawa
    • Journal Title

      Conference record on IEEE Nuclear Science Symposium and Medical Imaging Conference

      Volume: 1 Pages: 1-4

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] SPECTにおけるモンテカルロシミュレーション技術2018

    • Author(s)
      尾川浩一
    • Journal Title

      核医学技術

      Volume: 38 Pages: 112-119

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Simulation study on a stationary SPECT system with multi-pinhole collimators2017

    • Author(s)
      Hayao KUBOTA, Nobutoku MOTOMURA, Koichi OGAWA
    • Journal Title

      Conf Record on IEEE Nuclear Science Symposium and Medical Imaging Conference

      Volume: 1 Pages: 1-4

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] List mode reconstruction of a multi-pinhole triple head SPECT system2018

    • Author(s)
      Yohei Fujishiro, Hayao Kubota, Koichi Ogawa, Nobutoku Motomura
    • Organizer
      第115回日本医学物理学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] SPECTにおける画像再構成と画質の改善2018

    • Author(s)
      尾川浩一
    • Organizer
      応用物理学会放射線分科会シンポジウム
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 「次世代のCT技術を目指して ~フォトンカウンティング型X線CTと 静止型データ収集SPECT~」2017

    • Author(s)
      尾川浩一
    • Organizer
      Dual Energy CTセミナー 2017
    • Place of Presentation
      浦和コルソコミュニティプラザ7Fホール(埼玉県さいたま市)
    • Year and Date
      2017-03-18
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Imaging of Single Pinhole SPECT with a TEW Scatter Correction2017

    • Author(s)
      Xiaona Shan, Yutaro Hemuki, Koichi Ogawa
    • Organizer
      International Forum on Medical Imaging in Asia
    • Place of Presentation
      てんぶす那覇(沖縄県那覇市)
    • Year and Date
      2017-01-19
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Multi-pinhole imaging with a triple head SPECT system2017

    • Author(s)
      Hayao Kubota, Yutaro Hemuki, Koichi Ogawa, Nobutoku Motomura
    • Organizer
      第113回日本医学物理学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] ピンホールSPECTイメージング2017

    • Author(s)
      尾川浩一
    • Organizer
      第27回心臓核医学会学術大会(教育講演)
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] SPECTにおけるモンテカルロシミュレーション技術2017

    • Author(s)
      尾川浩一
    • Organizer
      第37回日本核医学技術学会学術大会シンポジウム
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Multi-pinhole SPECT system with a triple head gamma camera2016

    • Author(s)
      Hayao Kubota, Yutaro Hemuki, Nobutoku Motomura, Koichi Ogawa
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      convention center (France Strasbourg)
    • Year and Date
      2016-10-29
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Monte Carlo simulation for the multi- pinhole SPECT2016

    • Author(s)
      Yutaro Hemuki, Koichi Ogawa
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Related Report
      2016 Research-status Report
  • [Book] 画像・情報処理2018

    • Author(s)
      尾川浩一
    • Total Pages
      342
    • Publisher
      国際文献社
    • ISBN
      9784902590777
    • Related Report
      2017 Research-status Report
  • [Remarks]

    • URL

      http://www.ip.k.hosei.ac.jp/

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://ogawa-lab.info/

    • Related Report
      2018 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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