Validation study for administrative data

• Project/Area Number: 16K09043
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Juntendo University
• Principal Investigator: Nojiri shuko 順天堂大学, 革新的医療技術開発研究センター, 准教授 (80763466)
• Co-Investigator(Kenkyū-buntansha): 横山 和仁 順天堂大学, 医学部, 客員教授 (00158370) ; 後藤 景子 (平野 景子) 順天堂大学, 革新的医療技術開発研究センター, 准教授 (10772519) ; 伊藤 弘明 順天堂大学, 医学部, 助教 (30502257)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2017: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 高齢者 / レセプトデータベース / 臨床疫学 / 妥当性研究 / データベース / 合併症 / レセプトデータ

Outline of Final Research Achievements

We obtained anonymized electronic medical records and claim data for cardiology and ophthalmology from April 2010 to March 2011. Sensitivity and specificity of "acute myocardial infarction" and "cataract" in the injury name (ICD-10) on the receptor were determined by using the patient's true value as confirmed by a specialist on the electronic chart. In 360 cases of "acute myocardial infarction", 50 cases of "acute myocardial infarction" on the electronic medical record had a sensitivity of 72% and a specificity of 96.4%. Among 1,568 cases of "cataract", 1043 cases of "cataract" on the electronic medical record had a sensitivity of 92.5% and a specificity of 43.9%.

Academic Significance and Societal Importance of the Research Achievements

本研究では，単施設DPC病院にて、「急性心筋梗塞」および「白内障」などの妥当性検証を検討し、疾患誤分類がどの程度かを求めた。さらにGreenlandらのシミュレーション手法から疾患の誤分類バイアスがあった場合にアウトカムにどのぐらい影響があるかを検討し、その影響が大きいことを数量的に示した。さらに、応用事例としてオープンNDBを使った横断研究を循環器領域（カテーテル処置、睡眠時無呼吸症候群のc-papによる処置）、整形外科領域で実施した。

Research Products

• [Journal Article] National burden of the pharmaceutical cost of wet compresses and its cost predictors: nationwide cross-sectional study in Japan (2019)
  • Author(s): Itoh Hiroaki、Saito Tomoyuki、Nojiri Shuko、Hiratsuka Yoshimune、Yokoyama Kazuhito
  • Journal Title: Health Economics Review Volume: 9 Issue: 1 Pages: 20-20
  • DOI: 10.1186/s13561-019-0238-6
  • Peer Reviewed / Open Access
• [Presentation] Prefectural Variations in Numbers of Percutaneous Coronary Intervention Procedures in Japan: Data from the Open National Insurance Claims Database. (2018)
  • Author(s): 齋藤智之、葛西隆敏、野尻宗子、代田浩之
  • Organizer: 日本循環器学会
• [Presentation] Prefectural Variations in Numbers of Percutaneous Coronary Intervention Procedures in Japan: Data from the Open National Insurance Claims Database. (2018)
  • Author(s): 齋藤智之
  • Organizer: 日本循環器学会
• [Presentation] レセプト情報・特定健診等情報データベースオープンデータを用いた無呼吸症候群の実態把握 (2017)
  • Author(s): 齋藤 智之, 野尻 宗子, 平野 景子, 葛西 隆敏, 代田 浩之
  • Organizer: 日本睡眠学会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2017-06-29
• [Presentation] レセプト情報・特定健診等情報データベースオープンデータを用いた無呼吸症候群の実態把握 (2017)
  • Author(s): 齋藤智之
  • Organizer: 日本睡眠学会
• [Presentation] National burden of the pharmaceutical cost of wet compresses and the predictors of this cost: a cross-sectional study using nationwide health insurance claims data in Japan (2017)
  • Author(s): 伊藤弘明
  • Organizer: 日本公衆衛生学会