Five-year follow-up of the large-scale cohort study on vitamin D for the prevention of age- and lifestyle-related diseases

Research Project

Project/Area Number	16K09078
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Epidemiology and preventive medicine
Research Institution	Niigata University of Health and Welfare
Principal Investigator	saito toshiko 新潟医療福祉大学, 健康科学部, 教授 (40339958)
Co-Investigator(Kenkyū-buntansha)	中村和利新潟大学, 医歯学系, 教授 (70207869)
Project Period (FY)	2016-04-01 – 2020-03-31
Project Status	Completed (Fiscal Year 2019)
Budget Amount *help	¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000) Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000) Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000) Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	ビタミンD / コホート研究 / 加齢性疾患 / 生活習慣病 / 予防医学 / ビタミンＤ / 骨粗鬆症 / その他
Outline of Final Research Achievements	This study was conducted to determine blood 25-hydroxyvitamin D concentrations of 1044 subjects among participants of the 5-year follow-up investigation of the large-scale vitamin D cohort study. We identified predictors of vitamin D decline, including education, outdoor occupation, physical activity, and green tea consumption. We also found sex-difference in such association. In addition, information on new cases of age- and lifestyle-related diseases has been obtained.
Academic Significance and Societal Importance of the Research Achievements	加齢性疾患・生活習慣病予防の観点からビタミンDの重要性が世界的に注目されている。このような状況の下、私たちはビタミンD低下に関わる要因を縦断的に調査し特定した。本研究は大規模かつ縦断研究である点が評価され、British Journal of Nutrition誌に掲載が決定した。また本研究は地域住民の生活習慣に関連した要因を直接特定でき、一般住民の健康増進に有用な情報を提供できたことは社会的に意義深い。