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Spontaneous theory of mind in adults with ADHD and ASD

Research Project

Project/Area Number 16K10225
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Psychiatric science
Research InstitutionShowa University

Principal Investigator

Iwanami Akira  昭和大学, 医学部, 教授 (80276518)

Co-Investigator(Kenkyū-buntansha) 高塩 理  昭和大学, 医学部, 准教授 (00384256)
岡島 由佳  昭和大学, 医学部, 准教授 (50317525)
谷 将之  昭和大学, 医学部, 講師 (70384500)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords発達障害 / ASD / ADHD / アイトラッカー / 心の理論 / 視線計測 / 鑑別診断
Outline of Final Research Achievements

Spontaneous theory of mind (ToM) is an unconscious and automatic understanding of others’ mental states. Previous studies reported the impairment of spontaneous ToM in persons with ASD. None, to our knowledge, has investigated spontaneous ToM in adults with ADHD. We performed this study to examine implicit mentalizing in adults with ASD and ADHD using the anticipatory-looking paradigm designed by Senju et al (2009). The total fixation times to three areas of interest, i.e., the actor and the false-belief congruent and incongruent sides of the scene were measured. We found that both subjects with ADHD and controls did not show looking bias toward either the false-belief congruent or incongruent side, however, subjects with ADHD had significant bias. These results suggested the absence of looking bias to the false-belief incongruent side in both groups is indicative of intact implicit ToM in adults with ADHD.

Academic Significance and Societal Importance of the Research Achievements

成人期におけるADHDとASDは、しばしば類似した臨床像を示すため両者の鑑別が難しい。しかしながら現状では、診断に利用できる生物学的な指標は存在していない。本研究は、成人期のADHD とASD を臨床的に鑑別可能な生物学的指標を求めることを目的としている。このため、ADHD とASD の成人当事者を対象として、動画を視聴時におけるアイトラッカーによる視線計測を行なった。その結果、ASDと異なり、ADHDにおいては「心の理論」の機能が保持されていることが明らかになり、この障害が両者の鑑別点になる可能性を示した。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (18 results)

All 2019 2018 2017 2016

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 2 results) Presentation (10 results) (of which Int'l Joint Research: 6 results) Book (3 results)

  • [Journal Article] Clinical Characteristics of Women with ADHD in Japan2019

    • Author(s)
      Hayashi W, Suzuki H, Saga N, Arai G, Igarashi R, Tokumasu T, Ota H, Yamada H, Takashio O, Iwanami A
    • Journal Title

      .Neuropsychiatr Dis Treat

      Volume: 15 Pages: 3367-3374

    • DOI

      10.2147/ndt.s232565

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] ASDにおける非言語的誤信念動画課題遂行時における視線計測2018

    • Author(s)
      新井豪佑, 幾瀬大介, 徳増卓宏, 佐賀信之, 太田真里絵, 佐藤綾夏, 峯岸玄心, 川口佑, 岩波明
    • Journal Title

      精神科

      Volume: 33 Pages: 188-193

    • NAID

      40021604204

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] The effect of visual cues on performance in the ultimatum game in individuals with autism spectrum disorder.2018

    • Author(s)
      Ikuse D, Tani M, Itahashi T, Yamada H, Ohta H, Morita T, Arai G, Saga N, Tokumasu T, Ohta M, Sato A, Iwanami A.
    • Journal Title

      Psychiatry Res

      Volume: ;259: Pages: 176-183

    • DOI

      10.1016/j.psychres.2017.10.013

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Aberrant Spatial and Temporal Prefrontal Activation Patterns in Medication-Naïve Adults with ADHD2017

    • Author(s)
      Yamagata B, Takei Y, Itahashi T, Pu S, Hirano J, Mimura M, Iwanami A.
    • Journal Title

      Front Psychiatry

      Volume: 8 Pages: 1-8

    • DOI

      10.3389/fpsyt.2017.00274

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ADHDの薬物療法2016

    • Author(s)
      岩波明、徳増卓宏、佐賀信之
    • Journal Title

      精神科

      Volume: 29 Pages: 406-414

    • Related Report
      2016 Research-status Report
  • [Presentation] 日本における成人の注意欠如・多動症患者に対するグアンファシン徐放錠の安全性と有効性 フェーズ3オープンラベル長期投与試験2019

    • Author(s)
      岩波 明, 斎藤 万比古, 藤原 正和, 奥津 大樹, 市川 宏伸
    • Organizer
      日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会29回・49回
    • Related Report
      2019 Annual Research Report
  • [Presentation] ADHDの薬物療法と非薬物療法 成人期ADHDに対するGuanfacineの効果2019

    • Author(s)
      岩波 明
    • Organizer
      日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会29回・49回
    • Related Report
      2019 Annual Research Report
  • [Presentation] 成人期発達障害におけるADOS-2評価の検討2019

    • Author(s)
      花輪 洋一, 林 若穂, 青柳 啓介, 岩見 有里子, 太田 真里絵, 佐藤 綾夏, 新井 豪佑, 佐賀 信之, 太田 晴久, 岩波 明
    • Organizer
      第115回日本精神神経学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 成人発達障害における心理検査(SCI、TEG、P-Fスタディ)の特徴・傾向について2019

    • Author(s)
      西尾 崇志, 森井 智美, 太田 晴久, 大森 裕, 小島 睦, 花輪 洋一, 新井 豪佑, 森田 哲平, 佐藤 綾夏, 横山 佐知子, 武藤 奈奈, ロンバート はるみ, 飯田 優加, 金井 智恵子, 今村 薫奈, 内田 侑里香, 池ヶ谷 訓章, 加藤 進昌, 岩波 明
    • Organizer
      第115回日本精神神経学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Spontaneous theory of mind in adults with ADHD and ASD2018

    • Author(s)
      Iwanami A, Arai G, Tokumasu T, et al.
    • Organizer
      The International ADHD Congress 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Mind wandering in adults with ADHD2018

    • Author(s)
      Iwanami A, Arai G, Saga N, et al.
    • Organizer
      The International ADHD Congress 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] The ability of theory of mind in adults with ADHD2017

    • Author(s)
      Arai G, Saga N, Iwanami A
    • Organizer
      6th World Congress on ADHD
    • Place of Presentation
      Vancouver (Canada)
    • Year and Date
      2017-04-20
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Clinical characteristics of adults with ADHD2017

    • Author(s)
      Iwanami A. et al.
    • Organizer
      6th World Congress on ADHD
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Ability of Theory of Mind with Attention Deficit and Hyperactivity Disorders2017

    • Author(s)
      Arai G, Iwanami A, et al.
    • Organizer
      6th World Congress on ADHD
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Assessments of attentional functions in adults with ADHD2017

    • Author(s)
      Saga H, Iwanami A, et al.
    • Organizer
      6th World Congress on ADHD
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Book] 天才と発達障害2019

    • Author(s)
      岩波明
    • Total Pages
      253
    • Publisher
      文藝春秋社
    • Related Report
      2019 Annual Research Report
  • [Book] うつと発達障害2019

    • Author(s)
      岩波明
    • Total Pages
      221
    • Publisher
      青春出版社
    • ISBN
      9784413045735
    • Related Report
      2019 Annual Research Report
  • [Book] 発達障害2017

    • Author(s)
      岩波明
    • Total Pages
      255
    • Publisher
      文藝春秋社
    • ISBN
      9784166611232
    • Related Report
      2017 Research-status Report 2016 Research-status Report

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Published: 2016-04-21   Modified: 2021-02-19  

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