| Project/Area Number |
16K10281
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Hiroshima University |
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Principal Investigator |
Honda Yukiko 広島大学, 病院(医), 病院助教 (60604486)
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| Co-Investigator(Kenkyū-buntansha) |
亭島 淳 広島大学, 医歯薬保健学研究科(医), 准教授 (20397962)
安井 弥 広島大学, 医歯薬保健学研究科(医), 教授 (40191118)
檜垣 徹 広島大学, 医歯薬保健学研究科(医), 共同研究講座准教授 (80611334)
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | Dual-Energy CT / CT / Dual Energy / renal tumor / Fe / Dual Energy / エックス線 |
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| Outline of Final Research Achievements |
Purpose of this study is to evaluate image analysis of iron and fat and its clinical application for diagnosis of renal lesions by Dual-Energy CT(DECT). We used a phantom and a mixture of iron and fat. Using DECT, we separately identified iron and fat components in their mixtures, however, we cannot identify small amount of iron and fat. We also tried to distinguish between tumors with and without bleeding with high iron content, but there was no significant difference in the results because of inhomogeneous bleeding distribution.
Currently, from the acquired data, we cannot get significant difference results of its clinical application to renal tumor diagnosis.
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| Academic Significance and Societal Importance of the Research Achievements |
近年、Dual-Energy CT（DECT)が臨床機として普及してきたが。解析法や適応症例の選択基準は未だ明確ではない。また、各メーカーでDECTの構造が異なり、個々の機器の特性を熟知して、適応を検討しなければならない。我々の結果からは、DECTを、微小な鉄、脂肪解析が必要な腎病変診断に用いることは、現時点で尚早と言わざるを得ないが、研究から見出した問題点を示すことは、DECT発展の一助となる。
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