| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
The aim of this study is to establish animal model of cerebral aneurysm and to investigate its mechanisms using the animal model. Using 3T-MRI and coil for mouse head, we can image the arteries in mouse brain. In high cholesterol mice, the rapture of aneurysm increased rather than that in normal cholesterol mice. In plasminogen-knockout mice, the rapture of aneurysm reduced rather than that in control mice. This suggests that plasmin may be related with the rapture of aneurysm.
|
