Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Outline of Final Research Achievements |
Experiment 1:The purpose of this experiment was to investigate the effect of leukocyte-poor (LR) platelet-rich plasma (PRP) on potential healing of avascular zone of longitudinal medial meniscus tears in rabbit model. 0.5 mL of LR-PRP membrane from each rabbit’s whole blood was prepared and put into longitudinal tears with suture. We found that there were no significant differences of quantitative macroscopic and histologic scoring between LR-PRP group and control group at 12 weeks after surgery. Experiment 2:Based on the results of experiment 1, we changed the injury model from longitudinal tears to 1.5-mm circular defects, and formulation of PRP form membrane to clot. The results are currently being analyzed, and the results are expected to be published in the next year.
|