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Diffusion kurtosis imaging for oral carcinoma: predicting for nodal metastases

Research Project

Project/Area Number 16K11499
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionTokyo Medical and Dental University

Principal Investigator

SAKAMOTO Junichiro  東京医科歯科大学, 大学院医歯学総合研究科, 助教 (40506896)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords拡散強調画像 / 拡散尖度画像 / 口腔癌 / 浸潤 / 構造解析
Outline of Final Research Achievements

In this study, we had developed the DKI analysis in-house program, in which D-map and K-map were calculated and exported automatically. In the DKI study about the correlation between the pathological condition of primary site and DKI parameters in the oral carcinoma, this program was used and reliable results were obtained.
Also, we has performed the study about the correlation between prognosis of oral carcinoma and DKI parameters, retrospectively.

Academic Significance and Societal Importance of the Research Achievements

本研究にて開発された拡散尖度MRI解析プログラムによりMRIにて撮影された拡散強調画像よりDKI解析に用いる各パラメータマップ(D-mapおよびK- map)を自動作成でき、エクスポートが可能となった。このことにより、今ままで複雑な操作を必要としていた拡散強調画像解析が簡便なものとなり、より臨床へ利用しやすくなった。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (22 results)

All 2019 2018 2017 2016

All Journal Article (13 results) (of which Peer Reviewed: 11 results) Presentation (9 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Imaging the bifid mandibular canal using high resolution MRI2019

    • Author(s)
      Wamasing Peerapong、Deepho Chutamas、Watanabe Hiroshi、Hayashi Yoshiki、Sakamoto Junichiro、Kurabayashi Tohru
    • Journal Title

      Dentomaxillofacial Radiology

      Volume: 48 Issue: 3 Pages: 20180305-20180305

    • DOI

      10.1259/dmfr.20180305

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion kurtosis imaging of endometrial carcinoma: correlation with histopathological findings.2019

    • Author(s)
      Yamada I, Sakamoto J, Kobayashi D, Miyasaka N, Wakana K, Oshima N, Wakabayashi A, Saida Y, Tateishi U, Eishi Y.
    • Journal Title

      Magn Reson Imaging

      Volume: 57 Pages: 337-346

    • DOI

      10.1016/j.mri.2018.12.009

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diagnostic abilities of 3T MRI for assessing mandibular invasion of squamous cell carcinoma in the oral cavity: comparison with 64-row multidetector CT2019

    • Author(s)
      Suzuki Noriko、Kuribayashi Ami、Sakamoto Kei、Sakamoto Junichiro、Nakamura Shin、Watanabe Hiroshi、Harada Hiroyuki、Kurabayashi Tohru
    • Journal Title

      Dentomaxillofacial Radiology

      Volume: 48 Issue: 4 Pages: 20180311-20180311

    • DOI

      10.1259/dmfr.20180311

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Colorectal carcinoma: ex vivo evaluation using q-space imaging; correlation with histopathologic findings.2018

    • Author(s)
      Yamada I, Hikishima K, Yoshino N, Sakamoto J, Miyasaka N, Yamauchi S, Uetake H, Yasuno M, Saida Y, Tateishi U, Kobayashi D, Eishi Y.
    • Journal Title

      J Magn Reson Imaging

      Volume: 48 Issue: 4 Pages: 1059-1068

    • DOI

      10.1002/jmri.26018

    • Related Report
      2018 Annual Research Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Oral carcinoma: clinical evaluation using diffusion kurtosis imaging and its correlation with histopathologic findings.2018

    • Author(s)
      Yamada I, Yoshino N, Hikishima K, Sakamoto J, Yokokawa M, Oikawa Y, Harada H, Kurabayashi T, Saida Y, Tateishi U, Yukimori A, Izumo T, Asahina S.
    • Journal Title

      Magn Reson Imaging.

      Volume: 51 Pages: 69-78

    • DOI

      10.1016/j.mri.2018.04.014

    • Related Report
      2018 Annual Research Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Imaging findings of childhood B-cell lymphoblastic lymphoma in the mental region: a case report.2017

    • Author(s)
      Lam PD, Kuribayashi A, Sakamoto J, Nakamura S, Harada H, Kurabayashi T.
    • Journal Title

      Dentomaxillofac Radiol

      Volume: 46(3) Issue: 3 Pages: 20160313-20160313

    • DOI

      10.1259/dmfr.20160313

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 顎関節の疾患2017

    • Author(s)
      坂本潤一郎、Ngamsom Supak、栗林亜実、倉林 亨
    • Journal Title

      画像診断

      Volume: 37 Pages: 671-683

    • Related Report
      2017 Research-status Report
  • [Journal Article] The intravoxel incoherent motion MRI of lateral pterygoid muscle: a quantitative analysis in patients with temporomandibular joint disorders2017

    • Author(s)
      Ngamsom Supak、Nakamura Shin、Sakamoto Junichiro、Kotaki Shinya、Tetsumura Akemi、Kurabayashi Tohru
    • Journal Title

      Dentomaxillofacial Radiology

      Volume: 46 Issue: 5 Pages: 20160424-20160424

    • DOI

      10.1259/dmfr.20160424

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] A Case of Odontogenic Myxoma in which Magnetic Resonance Imaging Aided Diagnosis2017

    • Author(s)
      小滝 真也、坂本 潤一郎、浅井 桜子、栗林 亜実、鵜澤 成一、倉林 亨
    • Journal Title

      Shika Hoshasen

      Volume: 57 Issue: 1 Pages: 54-56

    • DOI

      10.11242/dentalradiology.57.54

    • NAID

      130006106551

    • ISSN
      0389-9705, 2185-6311
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] A Case of Ghost Cell Odontogenic Carcinoma in the Maxilla2017

    • Author(s)
      坂本 潤一郎、小滝 真也、中村 伸、角倉 可奈子、原田 浩之、倉林 亨
    • Journal Title

      Shika Hoshasen

      Volume: 57 Issue: 1 Pages: 57-59

    • DOI

      10.11242/dentalradiology.57.57

    • NAID

      130006106550

    • ISSN
      0389-9705, 2185-6311
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 最近の歯学 2. 口腔放射線医学 拡散強調MRIによる拡散・灌流評価:顎顔面領域への応用2016

    • Author(s)
      坂本潤一郎,倉林 亨
    • Journal Title

      口腔病学会雑誌

      Volume: 83 Pages: 88-88

    • Related Report
      2016 Research-status Report
  • [Journal Article] Diffusion tensor imaging of the inferior alveolar nerve using 3T MRI: a study for quantitative evaluation and fibre tracking.2016

    • Author(s)
      Kotaki S, Sakamoto J, Kretapirom K, Supak N, Sumi Y, Kurabayashi T.
    • Journal Title

      Dentomaxillofac Radiol.

      Volume: 45 Issue: 8 Pages: 2016200-2016200

    • DOI

      10.1259/dmfr.20160200

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Application of diffusion kurtosis imaging to odontogenic lesions: Analysis of the cystic component.2016

    • Author(s)
      Sakamoto J, Kuribayashi A, Kotaki S, Fujikura M, Nakamura S, Kurabayashi T.
    • Journal Title

      J Magn Reson Imaging

      Volume: 88(1049) Issue: 6 Pages: 1565-1571

    • DOI

      10.1002/jmri.25307

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 単純Volumetric interpolated breath-hold examination sequenceを用いた下歯槽神経血管束の描出能について2018

    • Author(s)
      渡邊裕, Chutamas Deepho, 坂本潤一郎, 倉林亨.
    • Organizer
      NPO法人日本歯科放射線学会第59回学術大会・第15回定例総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Utility of fusion volumetric images from computed tomography and magnetic resonance imaging for localizing the mandibular canal2018

    • Author(s)
      Chutamas Deepho, 渡邊裕, 坂本潤一郎, 倉林亨.
    • Organizer
      NPO法人日本歯科放射線学会第59回学術大会・第15回定例総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 歯科用金属によるアーチファクトへのWARP-VATの適応:ファントム実験による低減効果の検証2018

    • Author(s)
      Tran Thi Xuan Lan, 坂本潤一郎, 富里博, 倉林亨.
    • Organizer
      第46回日本磁気共鳴医学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 口腔扁平上皮癌におけるMRI-IVIMパラメータとFDG-PET/CTパラメータとの関連性の評価.2018

    • Author(s)
      中村伸, 鳥井原彰, 坂本潤一郎, 大山潤, 立石宇貴秀, 倉林亨.
    • Organizer
      第58回日本核医学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 子宮及び子宮内膜癌のDiffusion Kurtosis Imagingによる評価:病理組織学的所見との対比.2018

    • Author(s)
      山田一郎、坂本潤一郎、小林大輔、宮坂尚幸、若菜公雄、大島乃里子、若林晶、齋田幸久、立石宇貴秀、江石義信.
    • Organizer
      第77回日本医学放射線学会総会
    • Related Report
      2017 Research-status Report
  • [Presentation] 4D dynamic contrast-enhanced MRIの顎顔面領域へ の適応:TWISTシーケンス撮像パラメータの画質への影響2017

    • Author(s)
      坂本潤一郎, チャン チ スアン ラン, 富里 博, 羽田紘人, 戒田篤志, 倉林 亨
    • Organizer
      日本歯科放射線学会第58回学術大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Year and Date
      2017-06-03
    • Related Report
      2016 Research-status Report
  • [Presentation] 唾液腺腫瘍におけるIVIMとダイナミックMRI:パラメータの相関について.2017

    • Author(s)
      坂本潤一郎,ガンソムスパック,栗林亜実,鉄村明美,吉野教夫,中村 伸,倉林 亨.
    • Organizer
      日本歯科放射線学会第22回臨床画像大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Oral Carcinoma: Clinical Evaluation using Diffusion Kurtosis Imaging and its Correlation with Histopathologic Findings.2017

    • Author(s)
      Yamada I, Yoshino N, Hikishima K, Sakamoto J, Oikawa Y, Harada H, Kurabayashi T, Saida Y, Tateishi U, Izumo T, Asahina S.
    • Organizer
      The 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Colorectal Carcinoma: Ex Vivo Evaluation using q-Space Imaging and its Correlation with Histopathologic Findings.2017

    • Author(s)
      Yamada I, Hikishima K, Yoshino N, Sakamoto J, Miyasaka N, Yamauchi S, Uetake H, Yasuno M, Saida Y, Tateishi U, Kobayashi D, Eishi Y.
    • Organizer
      The 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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