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Visualization and quantification of diagnostic criteria and diagnosis for cevical adenopathy

Research Project

Project/Area Number 16K11536
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionFukuoka Dental College

Principal Investigator

Yuasa Kenji  福岡歯科大学, 口腔歯学部, 教授 (40136510)

Co-Investigator(Kenkyū-buntansha) 香川 豊宏  福岡歯科大学, 口腔歯学部, 准教授 (00258592)
三輪 邦弘  福岡歯科大学, 口腔歯学部, 講師 (10136509)
筑井 朋子 (白石朋子)  福岡歯科大学, 口腔歯学部, 講師 (80580472)
吉田 祥子  福岡歯科大学, 口腔歯学部, 助教 (90780635)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsoral cancer / cevical adnopathy / ultrasound / CT / MRI / 口腔癌 / 超音波検査 / 頸部リンパ節転移 / 悪性リンパ腫 / 頸部転移リンパ節 / 頸部リンパ節 / 悪性腫瘍
Outline of Final Research Achievements

Accuracy of the conventional diagnostic ultrasound criteria for cervical lymph node metastases was evaluated. As a result, a false-positive rate was very high. The need to add findings of shear wave elastograpy (SWE) was suggested. The shear wave velocity in metastatic lymph nodes was higher than non-metastatic lymph nodes significantly. Accuracy of differential diagnosis is very high. The vascular and scatter index were useful for differentiation with malignant lymphoma and the lymphadenitis. In addition, Enhanced findings of lymph node on CT and MRI, and the ADC value were useful for the differentiation of these lymph nodes. In follow-up duration, the optimal time interval of echographic examination is at least for one month for postoperative one year.

Academic Significance and Societal Importance of the Research Achievements

口腔癌患者において、ステージ分類に関わる頸部リンパ節転移を的確に検出することおよび術後の経過観察中の後発転移を早期に検出することは患者の予後に大きく反映する。その頸部リンパ節転移検出において重要な役割を担うのは超音波検査、CT、MRI等の画像診断である。本研究は、頸部リンパ節転移を超音波診断を中心とした画像診断基準の診断能の向上を目指す研究であるとともに、悪性リンパ腫と炎症性リンパ節腫大との鑑別を正確に行うための診断基準を作成するものであり、社会的意義は大きい。また、最新の画像診断技術を用いた診断基準の作成は学術的意義も大きい。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (18 results)

All 2020 2019 2018 2017 2016

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (14 results) Book (1 results)

  • [Journal Article] 口腔癌画像診断に役立つ知識 超音波2018

    • Author(s)
      湯浅賢治、三輪邦宏、香川豊宏、白石朋子、吉田祥子、橋本麻利江、松本妃可
    • Journal Title

      臨床画像

      Volume: 34 Pages: 1278-1288

    • Related Report
      2018 Research-status Report
  • [Journal Article] 口腔癌N0症例の頸部マネージメント 経過観察中の頸部リンパ節の超音波診断2016

    • Author(s)
      湯浅賢治、香川豊宏、白石朋子、三輪邦弘、山本千佳、吉田祥子
    • Journal Title

      日本口腔腫瘍学会誌

      Volume: 28 Pages: 57-64

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions.2016

    • Author(s)
      Tomoko Shiraishi, Toru Chikui, Kunihiro Miwa, Toyohiro Kagawa, Syouko Yoshida, Kenji Yuasa
    • Journal Title

      Oral Radiology

      Volume: 32 Issue: 2 Pages: 98-104

    • DOI

      10.1007/s11282-015-0219-3

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 頸部領域における超音波組織弾性映像法の走査像について2019

    • Author(s)
      三輪邦弘, 白石朋子, 吉田祥子, 橋本麻利江, 香川豊宏, 湯浅賢治
    • Organizer
      NPO法人日本歯科放射線学会第38回関西・九州合同地方会
    • Related Report
      2019 Annual Research Report 2018 Research-status Report
  • [Presentation] 頸部転移リンパ節の画像所見の検討2019

    • Author(s)
      橋本麻利江, 白石朋子, 吉田祥子, 三輪邦弘, 香川豊宏, 湯浅賢治
    • Organizer
      NPO法人日本歯科放射線学会第38回関西・九州合同地方会
    • Related Report
      2019 Annual Research Report 2018 Research-status Report
  • [Presentation] 舌癌と悪性リンパ腫が同時発生した1例2019

    • Author(s)
      福居朋子、吉田祥子、白石朋子、香川豊宏、西原有紀、三輪邦弘、湯浅賢治
    • Organizer
      NPO法人日本歯科放射線学会第39回関西・九州合同地方会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 炎症性筋線維芽細胞性腫瘍(IMT)3症例の画像所見2018

    • Author(s)
      白石朋子、吉田祥子、橋本麻利江、香川豊宏、松本妃可、三輪邦弘、湯浅賢治
    • Organizer
      NPO法人日本歯科放射線学会第23回臨床画像大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 頬隙に発生した腫瘍性病変の画像診断2018

    • Author(s)
      吉田祥子, 白石朋子, 香川豊宏,三輪邦弘, 橋本麻利江, 湯浅賢治
    • Organizer
      第72回NPO法人日本口腔科学会学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 頬部に発生した骨脂肪腫の画像所見2018

    • Author(s)
      橋本麻利江, 白石朋子, 吉田祥子, 松本妃可, 三輪邦弘, 香川豊宏, 湯浅賢治
    • Organizer
      NPO法人日本歯科放射線学会第23回臨床画像大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Shear Wave Elastographyの頭頸部転移リンパ節における有用性の検討2018

    • Author(s)
      白石朋子, 香川豊宏, 湯浅賢治
    • Organizer
      第36回日本口腔腫瘍学会総会・学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Diagnostic imaging for cervical lymph node metastasis in patients with oral cancer in our department2017

    • Author(s)
      Yuasa K., Kagawa T., Miwa K., Shiraishi T., Yoashida S.
    • Organizer
      The 23th International Association of Dento-Maxillo-Facial Radiology
    • Related Report
      2017 Research-status Report
  • [Presentation] MR imaging and ultrasound findings of neurogenic tumors in the head and neck region2017

    • Author(s)
      Yoashida S., Shiraishi T.,Kagawa T., Miwa K., Yuasa K.,
    • Organizer
      The 23th International Association of Dento-Maxillo-Facial Radiology
    • Related Report
      2017 Research-status Report
  • [Presentation] 頸部腫瘤性病変における超音波診断法の総合的評価2017

    • Author(s)
      三輪邦弘, 白石朋子, 吉田祥子, 香川豊宏, 杉野赳浩, 杉野真理子, 梅野悠太, 山野貴史, 湯浅賢治
    • Organizer
      第22回日本歯科放射線学会臨床画像大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 頭頸部転移リンパ節におけるShear Wave Elastographyの有用性2017

    • Author(s)
      白石朋子, 筑井徹, 香川豊宏, 三輪邦弘, 吉田祥子, 稲冨大介, 湯浅賢治
    • Organizer
      第58回日本歯科放射線学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] MR Imaging and Ultrasonography of Neurogenic Tumors in the Head and Neck Region.2017

    • Author(s)
      Yoshida S, Shiraishi T, Kagawa T, Miwa K, Yoshimoto S, Yuasa K
    • Organizer
      The 21th International Congress of Dental and Maxilla-Facial Radiology
    • Related Report
      2017 Research-status Report
  • [Presentation] Quantitative Shear Wave Elastography for the differentiation between Metastic and Inflammatory cervical lymph nodes.2016

    • Author(s)
      Tomoko Shiraishi, Toru Chikui, Kunihiro Miwa, Toyohiro Kagawa, Syouko Yoshida, Kenji Yuasa
    • Organizer
      The 11th Asian Congress of Oral and Maxillo-Facial Radiology
    • Place of Presentation
      Chiang Mai, Thailand
    • Year and Date
      2016-11-10
    • Related Report
      2016 Research-status Report
  • [Presentation] Diagnostic value of MR imaging for differentiating between ameloblastic carcinoma and benign odontogenic tumor2016

    • Author(s)
      Marie Hashimoto, Tomoko Shiraishi, Toyohiro Kagawa, Kunihiro Miwa, Koichi Yonetsu, Kenji Yuasa
    • Organizer
      The 11th Asian Congress of Oral and Maxillo-Facial Radiology
    • Place of Presentation
      Chiang Mai, Thailand
    • Year and Date
      2016-11-10
    • Related Report
      2016 Research-status Report
  • [Book] 歯科臨床における画像診断アトラス第2版2020

    • Author(s)
      日本歯科放射線学会編
    • Total Pages
      282
    • Publisher
      医歯薬出版株式会社
    • ISBN
      9784263458471
    • Related Report
      2019 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2021-02-19  

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