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Development and clinical application of optical diagnosis and pathological analysis for regressive changes of tooth structure

Research Project

Project/Area Number 16K11544
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionOkayama University

Principal Investigator

Shimada Yasushi  岡山大学, 医歯薬学総合研究科, 准教授 (60282761)

Co-Investigator(Kenkyū-buntansha) 北迫 勇一  東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (30361702)
高橋 礼奈  東京医科歯科大学, 歯学部附属病院, 助教 (40613609)
田上 順次  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (50171567)
Research Collaborator SUMI Yasunori  
SADR Alireza  
TABATA Tomoko  
ZHOU Yuan  
SEGARRA Michelle  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords亀裂 / エナメル質 / 光干渉断層計 / 咬合 / 微小亀裂 / 隣接面 / 脱灰 / コンポジットレジン / 光干渉断層系計 / 歯硬組織 / 咬耗 / 摩耗
Outline of Final Research Achievements

Enamel is hardest substance but brittle and prone to crack development. Enamel crack behavior on different areas of the teeth was evaluated using optical coherence tomography (OCT). Enamel crack behavior, in terms of crack pattern, location and direction, depended on its location on the tooth and tooth type.
Enamel cracks at enamel cavosurface margin of composite restorations were evaluated using OCT. OCT could detect enamel crack at the margins of composite restorations noninvasively. Presence and extent of enamel crack depended on the region for preparation and bonding protocol.
Interproximal contact areas of molars are susceptible to enamel cracks and dental caries in elderly people. Enamel microcracks with demineralization at proximal contact areas were evaluated using OCT. OCT could detect the micro-crack at interproximal contact area. Enamel microcracks significantly correlated with the demineralization lesion and may act as a confounding factor for proximal caries progression.

Academic Significance and Societal Importance of the Research Achievements

有歯列の高齢者では歯の亀裂や摩耗が顕在化し、予防と進行抑制に向けた対応を確立する必要がある。亀裂は位置と深さによって症状に変化がみられ、放置すると亀裂は象牙質に侵入し破折によって抜歯に至ることもある。したがって歯の亀裂の診断と予防法を確立する必要がある。
光干渉断層計(OCT)は光を用いて歯の精密な断層画像を得ることができ、放射線を用いずに小児や妊婦、高齢者の診断に安全に使用することができる。OCTを用いて歯の亀裂を観察した結果、歯の亀裂は部位によって形態や発生頻度が異なっていた。またストレスによってエナメル質に微小な亀裂が生じ、う蝕の発症と進行に影響を及ぼす可能性が示唆された。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (19 results)

All 2019 2018 2017 2016 Other

All Int'l Joint Research (3 results) Journal Article (6 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 6 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (10 results) (of which Int'l Joint Research: 6 results)

  • [Int'l Joint Research] university of Washington(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Washington(米国)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] ワシントン大学(米国)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Three-dimensional assessment of proximal contact enamel using optical coherence tomography2019

    • Author(s)
      Ei Thwe Zin、Shimada Yasushi、Abdou Ahmed、Sadr Alireza、Yoshiyama Masahiro、Sumi Yasunori、Tagami Junji
    • Journal Title

      Dental Materials

      Volume: 35 Issue: 4 Pages: e74-e82

    • DOI

      10.1016/j.dental.2019.01.008

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Assessment of root caries under wet and dry conditions using swept-source optical coherence tomography (SS-OCT)2018

    • Author(s)
      Zhou Yuan, Shimada Yasushi, Matin Khairul, Sadr Alireza, Yoshiyama Masahiro, Sumi Yasunori, Tagami Junji
    • Journal Title

      Dental Materials Journal

      Volume: 37 Issue: 6 Pages: 880-888

    • DOI

      10.4012/dmj.2017-273

    • NAID

      130007538075

    • ISSN
      0287-4547, 1881-1361
    • Year and Date
      2018-11-27
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Three-dimensional diagnosis of dentin caries beneath composite restorations using swept-source optical coherence tomography2018

    • Author(s)
      MATSUURA Chihiro、SHIMADA Yasushi、SADR Alireza、SUMI Yasunori、TAGAMI Junji
    • Journal Title

      Dental Materials Journal

      Volume: 37 Issue: 4 Pages: 642-649

    • DOI

      10.4012/dmj.2017-252

    • NAID

      130007421009

    • ISSN
      0287-4547, 1881-1361
    • Year and Date
      2018-07-26
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Assessment of enamel cracks at adhesive cavosurface margin using three-dimensional swept-source optical coherence tomography2017

    • Author(s)
      Tabata T, Shimada Y, Sadr A, Tagami J, Sumi Y
    • Journal Title

      Journal of Dentistry

      Volume: 61 Pages: 28-32

    • DOI

      10.1016/j.jdent.2017.04.005

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Three-Dimensional Analysis of Enamel Crack Behavior Using Optical Coherence Tomography2017

    • Author(s)
      Segarra MS, Shimada Y, Sadr A, Sumi Y, Tagami J
    • Journal Title

      Journal of Dental Research

      Volume: 96 Issue: 3 Pages: 308-314

    • DOI

      10.1177/0022034516680156

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Evaluation of resin infiltration on demineralized root surface: An <i>in vitro</i> study2017

    • Author(s)
      Zhou Y, Matin K, Shimada Y, Sumi Y, Tagami J
    • Journal Title

      Dental Materials Journal

      Volume: 36 Issue: 2 Pages: 195-204

    • DOI

      10.4012/dmj.2016-229

    • NAID

      130005519654

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] 3D diagnosis of proximal caries using swept-source optical coherence tomography.2018

    • Author(s)
      Shimada Y, Hosaka K, Araki K, Sadr A, Miyazaki T, Sumi Y, Tagami J, Yoshiyama M.
    • Organizer
      96th IADR General Session
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluating surface pre-etched glass ionomer filler containing materials against secondary caries.2018

    • Author(s)
      Zhou Y, Matin K, Shimada Y, Sumi Y, Tagami J.
    • Organizer
      96th IADR General Session
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cavity adaptation of composite restorations prepared at enamel surfaces and root dentin.2018

    • Author(s)
      Zakzouk R, Shimada Y, Zhou Y, Yoshiyama M, Sadr A, Sumi Y, Tagami J.
    • Organizer
      96th IADR General Session
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] C-factorが直接法コンポジットレジン修復の窩洞適合性に及ぼす影響.2018

    • Author(s)
      柏美砂,林樹莉,島田康史,Sadr Alireza,吉山昌宏,角保徳,田上順次.
    • Organizer
      日本歯科保存学会春季学術大会(第148回)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 3D imaging of dental caries using swept-source optical coherence tomography2017

    • Author(s)
      Shimada Y, Sadr A, Sumi Y, Tagami J, Yoshiyama M
    • Organizer
      The 19th JSCD/KACD Joint-Scientific Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 窩洞深度及び接着材の違いが窩洞底面の適合性に及ぼす影響2016

    • Author(s)
      袁楊、島田康史、周媛、角保徳、田上順次
    • Organizer
      日本歯科保存学会秋季学術大会(第145回)
    • Place of Presentation
      松本
    • Year and Date
      2016-10-27
    • Related Report
      2016 Research-status Report
  • [Presentation] コンポジットレジン修復周囲に生じたギャップの光干渉断層計観察2016

    • Author(s)
      ザクズークリマ、島田康史、周媛、角保徳、田上順次
    • Organizer
      日本歯科保存学会秋季学術大会(第145回)
    • Place of Presentation
      松本
    • Year and Date
      2016-10-27
    • Related Report
      2016 Research-status Report
  • [Presentation] 3D analysis of enamel crack using optical coherence tomography2016

    • Author(s)
      Segarra M, Shimada Y, Sadr A, Sumi Y, Tagami J
    • Organizer
      94th General Session & Exhibition of the IADR
    • Place of Presentation
      Soul
    • Year and Date
      2016-06-22
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Assessment of dental caries using swept-source optical coherence tomography in vivo2016

    • Author(s)
      Shimada Y, Hayashi J, Wada I, Aramaki O, Sadr A, Sumi Y, Tagami J
    • Organizer
      94th General Session & Exhibition of the IADR
    • Place of Presentation
      Soul
    • Year and Date
      2016-06-22
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 象牙質の部位とフロアブルレジンライニングが微小引張り接着強さならびに象牙質クラックに及ぼす影響2016

    • Author(s)
      高橋那緒,島田康史,ルンダオミングェド,角 保徳,田上順次
    • Organizer
      日本歯科保存学会春季学術大会(第144回)
    • Place of Presentation
      宇都宮
    • Year and Date
      2016-06-09
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2022-02-21  

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