| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
The superhydrophilic surface modification is reported to enhance the adsorption of the proteins to titanium. This study aimed to evaluate the binding behavior of LN332 on the surface-modified Ti with superhydrophilicity, In addition, the mechanism of enhancing adsorption of LN332 is considered by the surface analyses. The atmospheric-pressure plasma treatment (Ti-Plasma) and ultraviolet treatment (Ti-UV) as a superhydrophilic treatment were performed to the titanium sensor that was designed for quartz crystal microbalance (QCM-D) apparatus. Untreated gold (Au-Air) or titanium sensor (Ti-Air) were used as a control. Adsorption properties of LN332 were assessed using a QCM-D method. In addition, surface characteristics with X-ray photoelectron spectroscopy (XPS) and SEM observation are performed using LN332-adsrobed specimens.The results suggested that the superhydrophilic modifications may promote the adhesion of LN332 to titanium.
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