Strategic research for commercialization of new high functional materials for new concept of caries management system ICCMS
| Project/Area Number |
16K11820
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
ARITA Kenji 大阪歯科大学, 歯学部, 教授 (20168016)
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| Co-Investigator(Kenkyū-buntansha) |
篠永 ゆかり 大阪歯科大学, 歯学部, 講師 (70531961)
阿部 洋子 大阪歯科大学, 歯学部, 講師 (00325268)
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| Research Collaborator |
IRIE Masao
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | グラスアイオノマーセメント / ハイドロキシアパタイト / 機械的強度 / フッ化物イオン溶出 / ICCMS / イオン徐放能 / 抗菌性 |
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| Outline of Final Research Achievements |
The aim of this study was to clarify the reaction mechanism of new dental material, apatite ionomer cement (AIC) which glass ionomer cement to hydroxyapatite (HAp) was added to dental cement, glass ionomer cement (GIC). The following knowledge was obtained; 1) HAp is directly involved in the improvement of compression strength of AIC. 2) HAp is not involved in the fluoride ion release property of AIC and the amount are determined dependently on the P/L of GIC as a base material in AIC.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究において、新規AICの高強度で優れた各種イオン徐放能を有することが示されたことは，AICは歯質の脱灰抑制および再石灰化，中和作用・緩衝作用による生体親和性の向上，歯髄炎および歯肉炎の軽減，細菌付着およびプラーク形成の抑制，細菌の酸産生の抑制などの，優れたしかも高い機能性を示唆するものであり，本研究成果を礎に，AICが商品化されれば，旧来の”削って詰める”治療法から脱却でき，予防・口腔管理中心の“安全で優しい歯科医療”の達成が期待できる。
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Novel Multi-Functional Dental Cement for Enamel Remineralization and Anti-Cariogenic Bacteria Activity2018
Author(s)
Shinonaga Y, Arita K, Imataki R, Takemura M, Nagaishi C, Kagami K, Nishimura T, Abe Y, Aoki S, Okumura S, Harada K
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Journal Title
International Journal of Oral and Dental Health
Volume: 4
Issue: 2
Pages: 1-7
DOI
Related Report
Peer Reviewed / Open Access
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