Development of new comprehensive approaches for fracture using mechanical stress
Project/Area Number |
16K12933
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Kobe University |
Principal Investigator |
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Project Period (FY) |
2016-04-01 – 2019-03-31
|
Project Status |
Completed (Fiscal Year 2018)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 物理的刺激 / 骨折 / 骨粗鬆症 / 脆弱性骨折 / 超音波 / 電気刺激 / 体外衝撃波 / 超音波療法 / 電気刺激療法 / 物理療法 |
Outline of Final Research Achievements |
Although novel therapies for fracture or osteoporosis are constantly explored, effective and minimally invasive therapeutic approaches have not been established in clinical settings. In the present study, we aimed to develop a new comprehensive treatment for bone fracture, osteoporosis, and osteoporotic fracture using ultrasound, electrical stimulation, and extracorporeal shock wave. Our findings indicate that higher-intensity ultrasound promotes fracture healing, and that ultrasound, electrical stimulation, and extracorporeal shock wave were effective for osteoporosis. In addition, electrical stimulation and extracorporeal shock wave may be effective for promoting healing of osteoporotic fractures.
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Academic Significance and Societal Importance of the Research Achievements |
本研究により得られた知見から、超音波、電気刺激、体外衝撃波による物理的刺激が、骨折、骨粗鬆症、脆弱性骨折に対する新たな治療戦略になる可能性をもつことが示された。これらの治療法は、従来用いられている薬物療法や手術療法と比較すると、低侵襲的であり、経済的にも優れた技術・装置となり得る。
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Report
(4 results)
Research Products
(11 results)
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[Presentation] Radial extracorporeal shock wave therapy as potential treatment for osteoporosis2019
Author(s)
Inoue S, Yakuwa T, Suzuk R, Niikura T, Oe K, Fukui T, Nomura M, Wakimoto Y, Mizuno E, Li C, Kuroki H, Moriyama H
Organizer
13th International Society of Physical and Rehabilitation Medicine (ISPRM) World Congress
Related Report
Int'l Joint Research
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[Presentation] Radial extracorporeal shock wave therapy improves bone defect with osteoporosis in rats2019
Author(s)
Yakuwa T, Inoue S, Suzuki R, Niikura T, Oe K, Fukui T, Nomura M, Wakimoto Y, Mizuno E, Li C, Moriyama H
Organizer
13th International Society of Physical and Rehabilitation Medicine (ISPRM) World Congress
Related Report
Int'l Joint Research
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[Presentation] Effects of transcutaneous electrical stimulation on osteoporosis in ovariectomized rat2019
Author(s)
Inoue S, Yakuwa T, Suzuki R, Aoki H, Niikura T, Oe K, Fukui T, Nomura M, Wakimoto Y, Mizuno E, Li C, Moriyama H
Organizer
World Confederation for Physical Therapy (WCPT) Congress 2019
Related Report
Int'l Joint Research
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[Presentation] 骨折治癒を促進する至適な超音波強度の検討2018
Author(s)
鈴木崚太, 井上翔太, 八鍬匠, 李昌欣, 野村将人, 脇本祥夫, 水野絵里子, 木下紗英, 椿俊哉, 畠山隼平, 脇川大誠, 森山英樹
Organizer
第6回日本運動器理学療法学術大会
Related Report
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[Presentation] 超音波療法による新鮮骨折の治療促進効果の検討2017
Author(s)
鈴木崚太, 崎谷直義, 高野祥子, 島谷俊亮, 小笠原慎, 岩澤裕之, 野村将人, 脇本祥夫, 小原雄太, 水野絵里子, 森山英樹
Organizer
第52回日本理学療法学術大会
Related Report
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