| Project/Area Number |
16K15071
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Insect science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | カイコ / 脱皮 / 変態 / 幼若ホルモン / 脱皮ホルモン / ゲノム編集 / 実験形態学 / 昆虫 / 昆虫生理学 / 昆虫分子遺伝学 / 昆虫内分泌学 / ホルモン |
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| Outline of Final Research Achievements |
The purpose of this study is to investigate the reason why very young silkworm larvae are incompetent to metamorphosis. For this, we performed implantation assays using the very young larvae and found that when the integuments of neonate larvae were implanted into last instar host larvae, they are able to directly produce pupal cuticle at the time of pupal metamorphosis of the host. In addition, we found that body size is a key factor for the acquisition of competence for metamorphosis. Our results suggest that the tissues of very early instar larvae can metamorphose when provided with unidentified blood-borne factor(s) present in final-instar larvae, and that juvenile hormones can block the action of that factor(s) to prolong the feeding period until larvae attain a certain body size for metamorphosis.
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