| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Mosquito-vectored viral infections such as dengue and chikungunya fevers are recently expanding their original habitats and becoming new threats as emerging diseases in the naive countries. It is difficult to distinguish one from others by symptoms alone without using the modern molecular techniques. This fact is hindering the development of effective counter measures against these viral infections. The specific diagnostic system for dengue virus is already established by detecting NS1 antigens. We targeted chikungunya structural proteins for developing a rapid diagnostic system. The chikungunya virus was isolated from the specimens collected during its outbreak, and then its full-genome sequence analysis was completed. Based on these data, we have succeeded in establishing mouse monoclonal antibodies by which chikungunya virus can be detected on an immunochromatography strip.
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