| Project/Area Number |
16K15792
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Fukuoka Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
永尾 潤一 福岡歯科大学, 口腔歯学部, 講師 (30509047)
成田 由香 福岡歯科大学, 口腔歯学部, 助教 (50758050)
長 環 福岡歯科大学, 口腔歯学部, 教授 (90131870)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 歯学 / 免疫学 / 微生物学 / 細菌 / 細胞・組織 / 微生物 |
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| Outline of Final Research Achievements |
Dental caries are infectious diseases caused by paticular pathogenetic bacteria resident in the oral cavity. Prevention of dental caries is nothing less than preventing these bacteria from adhering to tooth surfaces. Antibodies are contained in saliva and caries can be prevented by them if it can increase the amount of antibodies targeting these bacteria. In this study, we focused on T cells and explored the epitopes of pathogenetic bacteria, aiming at the development of vaccines to prevent dental caries. Thus, this research is expected to develop into the development of a new-generation vaccine for dental caries prevention.
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