Analysis of neural basis of mate-guarding behavior using medaka fish.
| Project/Area Number |
16K18369
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology / General neuroscience
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| Research Institution | Hokkaido University |
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Principal Investigator |
Yokoi Saori 北海道大学, 薬学研究院, 助教 (10772048)
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 配偶者防衛行動 / 不安定化ドメイン / バソプレシン / 配偶者選択 / 行動学 / 配偶者防衛 / メダカ / 神経基盤 |
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| Outline of Final Research Achievements |
Mate-gurading behavior is induced by triadic relationships (two males and one female) and is observed in various animals. I previously found that vasopressin, which is one of neuropeptides, regulated mate-guarding behavior in medaka fish. Which neuron in the brain was necessary for inducing the behavior, however, is unknown. Therefore, I established the new methods in which I suppressed neural activity in some specific regions of the brain in a low molecular weight compound specific manner. In addition, we focused on female mating preference in medaka and revealed that long lasting mate-guarding increased the reproductive success of dominant males via disturbing visual interaction between the female and rival males.
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| Academic Significance and Societal Importance of the Research Achievements |
低分子化合物の有無により時期特異的に遺伝子発現を制御する方法はマウスなどの哺乳類ではすでに確立されているが、同様の手法がメダカで使用できない、あるいは着目する行動によっては投与物質の性質的に問題がある、という問題があった。本研究で確立した方法はこうした問題をクリアしており、毒性も低いことが明らかになった。また、これまでメダカのメスが見知ったオスを配偶相手として選択する適応的意義は不明であったが、本結果により、配偶者防衛行動において優位となる、健康なオスの子孫を残すことができるというメリットがあると考えられた。
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Report
(4 results)
Research Products
(19 results)
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[Presentation] Analysis of molecular basis underlying decision making according to social familiarity in small fish, medaka2017
Author(s)
Saori Yokoi, Satoshi Ansai, Yasuhiro Kamei, Masato Kinoshita, Yoshihito Taniguchi, Larry J. Young, Teruhiro Okuyama, Takeo Kubo, Kiyoshi Naruse, Hideaki Takeuchi
Organizer
IBNS 2017
Related Report
Int'l Joint Research / Invited
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[Book] めだかの学校2018
Author(s)
宗宮弘明、足立守、野崎ますみ、成瀬清
Total Pages
314
Publisher
あるむ
ISBN
9784863331334
Related Report
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