| Project/Area Number |
16K19042
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General medical chemistry
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
Abe Takaya 国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, 研究員 (10720609)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 心臓前駆細胞 / ゲノムバーコーディング / 細胞系譜解析 / 心臓発生 / CRISPR / 心外膜前駆細胞 |
|---|
| Outline of Final Research Achievements |
The morphogenesis of the heart is complicated and the origin of the cells that make up the heart has not yet been clarified, because it is very difficult to analyze the phenomenon with existing methods. To overcome this problem, I'm trying to develop a novel method, which allow us to trace whole cells. In this program, I succeeded in establishing the cell lineage tracing mice with mouse genetic engineering. I'm planning to further analyze using these mice in the future.
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