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Examination of choking risk in elderly with sarcopenia

Research Project

Project/Area Number 16K19262
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Epidemiology and preventive medicine
Research InstitutionNihon University

Principal Investigator

NAKAYAMA Enri  日本大学, 歯学部, 准教授 (10614159)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsサルコペニア / 高齢者 / 窒息 / 口腔機能 / 咀嚼 / 嚥下 / 嚥下障害 / 摂食嚥下障害 / 口唇閉鎖圧 / 舌圧 / 摂食嚥下機能 / 咀嚼機能
Outline of Final Research Achievements

In this study, we investigated the relationship between sarcopenia (a condition in which skeletal muscle mass and muscle strength are weakened), which affects many elderly people, and asphyxia. First, in a questionnaire survey conducted at nursing homes in Tokyo, Chiba, Osaka, and Aichi, 88% of the residents who had choked during meals at the facility had suspected sarcopenia. In addition, when the relationship between sarcopenia, lip closure and tongue pressure was investigated, it was suggested that sarcopenia may weaken these. It is known that both lip closing force and tongue pressure are related to masticatory ability, and decreased masticatory ability can be one of the causes of asphyxia. Therefore, sarcopenia may reduce oral function and become a risk factor for asphyxia. These results suggested that sarcopenia may cause a risk factor of asphyxia due to the decreased oral function.

Academic Significance and Societal Importance of the Research Achievements

窒息で亡くなる方が年々増加しているが、窒息の要因については未だ不明な点が多い。窒息で亡くなる方の大多数が高齢者であることを鑑みると、高齢者特有の機能低下が背景にあると考えた。そこで、本研究では高齢者の多くが罹患しているサルコペニアに着目し、サルコペニアと窒息との関連性について検討した。その結果、介護施設内で窒息を経験した入所者のほとんどがサルコペニアの疑いがあること、サルコペニアによって口腔機能が低下する可能性を認めたことから、サルコペニアが窒息の要因となる可能性が示唆された。以上のことから、本研究によりサルコペニアに罹患する高齢者を減らすことによって、窒息事故を減らせる可能性が示された。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (22 results)

All 2020 2019 2018 2017

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (10 results) (of which Int'l Joint Research: 3 results) Book (6 results)

  • [Journal Article] Effects of bolus consistency and reclining position on kinematic swallowing events in analysis using 320-row area detector computed tomography2020

    • Author(s)
      Tsuzuki H, Inamoto Y, Saitoh E, Aihara K, Shibata S, Kagaya H, Onogi K, Nakayama E, Sato M, Ueda K
    • Journal Title

      Journal of Oral Science

      Volume: 62 Issue: 1 Pages: 18-22

    • DOI

      10.2334/josnusd.18-0377

    • NAID

      130007791608

    • ISSN
      1343-4934, 1880-4926
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The periodontopathic bacterium Fusobacterium nucleatum induced proinflammatory cytokine production by human respiratory epithelial cell lines and in the lower respiratory organs in mice.2019

    • Author(s)
      Hayata M, Watanabe N, Tamura M, Kamio N, Tanaka H, Nodomi K, Miya C, Nakayama E, Ueda K, Ogata Y, Imai K
    • Journal Title

      Cellular Physiology and Biochemistry

      Volume: 53 Issue: 1 Pages: 49-61

    • DOI

      10.33594/000000120

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diagnostic accuracy of lip force and tongue strength for sarcopenic dysphagia in older inpatients: a cross-sectional observational study2019

    • Author(s)
      Kotomi Sakai, Enri Nakayama, Haruka Tohara, Osamu Takahashi, Sayako Ohnishi, Hidetaka Tsuzuki, Mayumi Hayata, Takahiro Takehisa, Yozo Takehisa, Koichiro Ueda
    • Journal Title

      Clinical Nutrition

      Volume: 38 Issue: 1 Pages: 303-309

    • DOI

      10.1016/j.clnu.2018.01.016

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Low-intensity pulsed ultrasound induces cartilage matrix synthesis and reduced MMP13 expression in chondrocytes2018

    • Author(s)
      Jumpei Sekino, Mayu Nagao, Shunichiro Kato, Mayu Sakai, Kimiko Abe, Enri Nakayama, Mitsuyasu Sato, Yuki Nagashima, Haruka Hino, Natsuko Tanabe, Takayuki Kawato, Masao Maeno, Naoto Suzuki, Koichiro Ueda
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 506 Issue: 1 Pages: 290-297

    • DOI

      10.1016/j.bbrc.2018.10.063

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationship between tongue strength, lip strength, and nutrition-related sarcopenia in older rehabilitation inpatients: a cross-sectional study2017

    • Author(s)
      Sakai K, Nakayama E, Tohara H, Kodama K, Takehisa T, Takehisa Y, Ueda K
    • Journal Title

      Clin Interv Aging

      Volume: 12 Pages: 1207-1214

    • DOI

      10.2147/cia.s141148

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tongue Strength is Associated with Grip Strength and Nutritional Status in Older Adult Inpatients of a Rehabilitation Hospital.2017

    • Author(s)
      Kotomi Sakai, Enri Nakayama, Motonobu Sugimoto, Haruka Tohara, Takahiro Takehisa, Tomomi Maeda, Yozo Takehisa, Koichiro Ueda.
    • Journal Title

      Dysphagia

      Volume: 32 Issue: 2 Pages: 241-249

    • DOI

      10.1007/s00455-016-9751-5

    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 誤嚥性肺炎により入院した患者の日常生活自立度および血中アルブミン値と経口摂取再開の予後との関係2019

    • Author(s)
      木村将典、稲川元明、小川祐介、中山渕利、飯田貴俊、小川哲史
    • Organizer
      第34回日本静脈経腸栄養学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] サルコペニアによる嚥下障害患者の嚥下機能の回復過程の一例2019

    • Author(s)
      中山渕利、日野多加美、大嶋晶子、戸原玄、植田耕一郎
    • Organizer
      第25回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 経口摂取状況と口腔アセスメントの関連性についての検討2019

    • Author(s)
      日野多加美、中山渕利、大嶋晶子、原豪志、山口浩平、戸原玄
    • Organizer
      第25回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Characteristics of Sarcopenic Dysphagia: Measurement of Suprahyoid Muscle Activity Using Surface Electromyography2019

    • Author(s)
      Kotomi Sakai, Enri Nakayama, Nicole Rogus-Pulia, Kevin Urayama, Koichiro Ueda Takahiro Takehisa, Yozo Takehisa, Osamu Takahashi
    • Organizer
      the 26th Annual DRS Meeting
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] サルコペニアによる嚥下障害患者の舌骨および甲状軟骨の移動距離の経時変化2018

    • Author(s)
      中山渕利、戸原玄、木村将典、渡邉真央、大嶋晶子、日野多加美、植田耕一郎
    • Organizer
      第24回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 表面筋電図を使用した嚥下中の筋活動時間とサルコペニア嚥下障害の関連-A pilot study2018

    • Author(s)
      堺琴美、中山渕利、Nicole Rogus-Pulia、Kevin Urayama、武久洋三、植田耕一郎、高橋理
    • Organizer
      第24回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] サルコぺニアによる嚥下障害患者に対し、回復期退院後も継続した栄養サポートが有効であった一症例2018

    • Author(s)
      大嶋晶子、中山渕利、日野多加美、石橋尚基、木皿歩、山口浩平、原豪志、戸原玄
    • Organizer
      第24回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] The relationship between tongue and lip strength and sarcopenic dysphagia2018

    • Author(s)
      Kotomi Sakai, Enri Nakayama, Haruka Tohara, Osamu Takahashi, Sayako Ohnishi, Hidetaka Tsuzuki, Mayumi Hayata, Takahiro Takehisa, Yozo Takehisa, Koichiro Ueda
    • Organizer
      the 26th Annual DRS Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Sarcopenia Score is Associated with Tongue Strength and Dysphagia2017

    • Author(s)
      Kotomi Sakai, Enri Nakayama, Haruka Tohara, Keiji Kodama, Kyoko Shikaura, Yoko Shimura, Hiroshi Irisawa, Motonobu Sugimoto, Takahiro Takehisa, Yozo Takehisa, Koichiro Ueda
    • Organizer
      the 25th Anniversary DRS Annual Meeting
    • Place of Presentation
      Oregon (U.S.A)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 食事中に窒息経験のある要介護高齢者の特徴2017

    • Author(s)
      中山渕利、植田耕一郎
    • Organizer
      第23回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2017 Research-status Report
  • [Book] 歯科衛生士のための口腔ケアと摂食嚥下リハビリテーション 改訂版2019

    • Author(s)
      中山渕利、植田耕一郎、坂口英夫、糸田昌隆、粟屋剛、今井美季子、尾崎研一郎、貴島真佐子、寺本浩平、西村智子、原豪志、横山雄士、蓜島桂子
    • Total Pages
      239
    • Publisher
      一般社団法人 口腔保健協会
    • ISBN
      9784896053562
    • Related Report
      2019 Annual Research Report
  • [Book] 新版 歯学生のための摂食嚥下リハビリテーション学2019

    • Author(s)
      中山渕利、向井美惠、山田好秋、井上誠、弘中祥司、齋藤一郎、石田瞭、村田尚道、藤谷順子、香取幸夫、渡邉裕、寺尾豊、野崎園子、野本たかと、野原幹司、戸原玄、清水充子、米山武義
    • Total Pages
      291
    • Publisher
      医歯薬出版株式会社
    • ISBN
      9784263458402
    • Related Report
      2019 Annual Research Report
  • [Book] 最新歯科衛生士教本 用語集2019

    • Author(s)
      中山渕利、合場千佳子、青山旬、赤川安正、秋山茂久、麻賀多美代、朝田芳信、麻生智子、安彦善裕、阿部昌子、阿部伸一、阿部仁子、天野修、新井一仁、荒川浩久、荒木美穂、飯島洋一、五十嵐順正、池田通、池田利恵
    • Total Pages
      320
    • Publisher
      医歯薬出版株式会社
    • ISBN
      9784263428528
    • Related Report
      2018 Research-status Report
  • [Book] よくわかる高齢者歯科2018

    • Author(s)
      中山渕利、阿部仁子、阿部倉仁、飯田崇、石田瞭、市川哲雄、井上誠、猪原健、大岡貴史、岡田芳幸、柏崎晴彦、北川昇、呉本晃一、小林琢也、小松知子、阪口英夫、菅武雄、鈴木史彦、角保徳、竹内一夫、田中陽子
    • Total Pages
      231
    • Publisher
      永末書店
    • ISBN
      9784816013393
    • Related Report
      2018 Research-status Report
  • [Book] デンタルスタッフの口腔衛生学・歯科衛生統計2018

    • Author(s)
      中山渕利、泉福英信、小川祐司、佐藤勉、粟野秀慈、相田潤、植田耕一郎、小関健由、小川智久、原節宏、吉田明弘、高橋信博、中尾龍馬、小方頼昌、岸光男、金本大成、伊藤博夫、野村義明、五味一博、長野孝俊
    • Total Pages
      265
    • Publisher
      医歯薬出版株式会社
    • ISBN
      9784263422465
    • Related Report
      2018 Research-status Report
  • [Book] 摂食嚥下障害リハビリテーション ABC2017

    • Author(s)
      中山渕利
    • Total Pages
      246
    • Publisher
      全日本病院出版会
    • ISBN
      9784865194142
    • Related Report
      2017 Research-status Report

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Published: 2016-04-21   Modified: 2021-02-19  

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