Research Project
Grant-in-Aid for Young Scientists (B)
1.We assessed the role of JCAD in the regulation of thrombus formation. Using IVC ligation model, we compared the DVT size between WT mice and JCAD knock out mice. JCAD knock-out mice exhibited significantly larger thrombus size compared to WT mice.2. We then assessed the molecular mechanism of JCAD in thrombus formation. Western blotting analysis revealed that JCAD regulate the ERK signaling cascade in HUVEC after the VEGF (vascular endothelial growth factor) stimulation.
All 2017
All Journal Article (1 results) (of which Peer Reviewed: 1 results)
Arteriosclerosis, Thrombosis, and Vascular Biology
Volume: 37 Issue: 9 Pages: 1667-1673
10.1161/atvbaha.117.309721