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Examination of factors related to long and med term clinical outcomes with PCI .

Research Project

Project/Area Number 16K19435
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Cardiovascular medicine
Research InstitutionFukuoka University

Principal Investigator

Ike Amane  福岡大学, 医学部, 講師 (00609498)

Research Collaborator Matsuoka Yuta  
Nakamura Masayuki  
Gondou Kouki  
Sirai Kazuyuki  
Saku keijiro  
Miura Shin-ichiro  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords経皮的冠動脈形成術 / レジストリー研究 / 薬剤溶出性ステント / 循環器・高血圧 / 臨床 / 臨床成績
Outline of Final Research Achievements

During this research period, I submitted three English papers with peer reviews which were later published, and also made more than one research presentation inside and outside Japan including a high-visibility international meeting in Europe. Fu-Registry, the base of this research, has been respectively registering and accumulating as data the backgrounds, lesion backgrounds and follow up results of the cases in which percutaneous coronary intervention was performed at each concerned facilities and Fukuoka University Hospital.
During this period, We registered 1,000 cases additionally, making our database as big as 3,574 cases in total. Among others, Fu-Registry is rare in that the quantitative and qualitative comparative analyses of each coronary arteriographic finding are carefully conducted mainly by doctors and then quantified. We will continue to accumulate data and present research results inside and outside Japan.

Academic Significance and Societal Importance of the Research Achievements

本研究の目的はPCIが施行された症例のDataを詳細に収集し数値化、データベース化する事によって治療成績に関与する因子を明らかにする事である。今回、期間内に3つの英語論文を発表した。①現在PCIの主流は薬剤溶出性ステント留置であるが、3.08mm以上の冠血管径があればBare Metal stentでも同等の成績が期待できる。②安定狭心症ではLDL-C 値が、non-HDL-C 値あるいは LDL-C と non-HDL-C の不一致性等より、臨床予後の重要な指標である。③冠動脈疾患2次予防の脂質管理目標値に性差は設定されていないが、各脂質関連因子とPCI後の治療成績の関連性には性差がある。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (16 results)

All 2019 2018 2017

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 4 results) Presentation (11 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Correction to: Association between discordance of LDL-C and non-HDL-C and clinical outcomes in patients with stent implantation: from the FU-Registry (Heart and Vessels, (2018), 33, 2, (102-112), 10.1007/s00380-017-1036-x)2018

    • Author(s)
      Shiiba Michiyo、Zhang Bo、Miura Shin-ichiro、Ike Amane、Nose Daisuke、Kuwano Takashi、Imaizumi Satoshi、Sugihara Makoto、Iwata Atushi、Nishikawa Hiroaki、Kawamura Akira、Shirai Kazuyuki、Yasunaga Shin’ichiro、Saku Keijiro
    • Journal Title

      Heart and Vessels

      Volume: 34 Issue: 1 Pages: 197

    • DOI

      10.1007/s00380-018-1123-7

    • URL

      https://pure.teikyo.jp/en/publications/37ff22f0-f6b5-473d-885e-4d77dc6680a0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sex difference between target levels of cholesterol-related parameters and post-PCI long-term clinical outcomes: From the FU-Registry2018

    • Author(s)
      Matsuoka Yuta、Ike Amane、Ogawa Masahiro、Gondo Kouki、Shirai Kazuyuki、Sugihara Makoto、Nose Daisuke、Nishikawa Hiroaki、Iwata Atsushi、Kawamura Akira、Mori Ken、Zhang Bo、Yasunaga Shin’ichiro、Miura Shin-ichiro、Saku Keijiro
    • Journal Title

      Journal of Cardiology

      Volume: 71 Issue: 3 Pages: 259-267

    • DOI

      10.1016/j.jjcc.2017.09.011

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between discordance of LDL-C and non-HDL-C and clinical outcomes in patients with stent implantation: from the FU-Registry2017

    • Author(s)
      Shiiba Michiyo、Zhang Bo、Miura Shin-ichiro、Ike Amane、Nose Daisuke、Kuwano Takashi、Imaizumi Satoshi、Sugihara Makoto、Iwata Atushi、Nishikawa Hiroaki、Kawamura Akira、Shirai Kazuyuki、Yasunaga Shin’ichiro、Saku Keijiro
    • Journal Title

      Heart and Vessels

      Volume: 33 Issue: 2 Pages: 102

    • DOI

      10.1007/s00380-017-1036-x

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Is a bare-metal stent still useful for improving the outcome of percutaneous coronary intervention? From the FU-Registry2017

    • Author(s)
      GONDO, K., IKE, A., OGAWA, M., SHIRAI, K., SUGIHARA, M., NISHIKAWA, H., IWATA, A., KAWAMURA, A., MORI, K., ZHANG, B., MIURA, S., YASUNAGA, S. & SAKU, K.
    • Journal Title

      J Cardiol

      Volume: 69 Issue: 4 Pages: 652-659

    • DOI

      10.1016/j.jjcc.2016.06.009

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ベアメタルステント(BMS)と薬剤溶出性ステント(DES):BMSの有効性について2017

    • Author(s)
      池 周而
    • Journal Title

      Research

      Volume: 21(3) Pages: 14-18

    • Related Report
      2016 Research-status Report
  • [Presentation] Combination of the Levels of Low-Density Lipoprotein Cholesterol and Non-High-Density Lipoprotein Cholesterol before Coronary Intervention is associated with Cardiac Events2019

    • Author(s)
      Amane Ike
    • Organizer
      第84回日本循環器学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Gender Differences with regard to “Obesity Paradox” in Clinical Outcomes after Percutaneous Coronary Intervention: FU-Registry2019

    • Author(s)
      Noriyuki Mouri, Amane ike
    • Organizer
      第84回日本循環器学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] coronary intervention (PCI) among 3 generations of stents2018

    • Author(s)
      Masayuki Nakamura, Amane Ike
    • Organizer
      第32回日本冠疾患学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Significant differences in lipid profile associated with major adverse cardiovascular events(MACEs) between hemodialysis(HD) and non-HD patients: from FU-registry2018

    • Author(s)
      Amane Ike
    • Organizer
      86th EAS Congress, Lisbon
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Sex difference between target levels of cholesterol-related parameters and post-PCI long-term clinical outcomes: From the FU-Registry.2018

    • Author(s)
      Yuta Matsuoka
    • Organizer
      86th EAS Congress, Lisbon
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Sex difference between target levels of cholesterol-related parameters and post-PCI long-term clinical outcomes: From the FU-Registry.2018

    • Author(s)
      Yuta Matsuoka
    • Organizer
      1st Asia-Pacific CardioMetabolic Syndrome Congress
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Is Bigger Still Better in Drug-eluting Stent Era? From the FU-registry2018

    • Author(s)
      Shirai Kazuyuki
    • Organizer
      第82回日本循環器学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Associations between five-years clinical outcomes and Chronic kidney disease (CKD) patients with Diabetes (DM) undergoing percutaneous coronary intervention (PCI) : From the FU-Registry.2018

    • Author(s)
      Amane Ike
    • Organizer
      第82回日本循環器学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Differential contributing factors for in-stent restenosis (ISR) after percutaneous coronary intervention (PCI) among 3 generations of stents2018

    • Author(s)
      Masayuki Nakamura
    • Organizer
      第82回日本循環器学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Association between New Target of Lipid Parameters and Long-term Clinical Outcomes after Percutaneous Coronary Intervention (PCI) in Patients with Diabetes Mellitus (DM): From Fu-Registry.2018

    • Author(s)
      Yuta Matsuoka
    • Organizer
      第82回日本循環器学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Examination about the Association of Lipid Parameters and Long termClinical Outcomes after2017

    • Author(s)
      松岡優太
    • Organizer
      日本循環器学会総会
    • Place of Presentation
      石川県音楽堂
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2020-03-30  

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