| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Outline of Final Research Achievements |
We performed a comprehensive mutation analysis of the synaptotagmin gene family in schizophrenic patients with drug-induced parkinsonisms. We found a novel heterozygous mutation, c.-18+47G/A, in intron 4 of the Synaptotagmin 1 gene in a patient with drug-induced dystonia.
In addition, we found different patterns of drug-induced parkinsonisms in 22q11.2 deletion syndrome patients with schizophrenia-like psychosis.
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